2.02012-05-31 10:27:09 -06002015-09-13 15:15:19 -0600ECMDB00516M2MDB000145b-D-GlucoseB-D-glucose is a member of the chemical class known as Hexoses. These are monosaccharides in which the sugar unit is a hexose. Glucose (C6H12O6, also known as D-glucose, dextrose, or grape sugar) is a simple sugar (monosaccharide) and an important carbohydrate in biology. Cells use it as the primary source of energy and a metabolic intermediate. Glucose is one of the main products of photosynthesis and fuels for cellular respiration. Glucose exists in several different molecular structures, but all of these structures can be divided into two families of mirror-images (stereoisomers). Only one set of these isomers exists in nature, those derived from the right-handed form of glucose, denoted D-glucose. D-glucose is sometimes referred to as dextrose, although the use of this name is strongly discouraged. The term dextrose is derived from dextrorotatory glucose. This name is therefore confusing when applied to the enantiomer, which rotates light the opposite direction. Starch and cellulose are polymers derived from the dehydration of D-glucose. The other stereoisomer, called L-glucose, is hardly ever found in nature. (WikiPedia)β-D-glucopyranoseβ-glucose6-(Hydroxymethyl)tetrahydropyran-2,3,4,5-tetraolB-D-Glucopyranoseb-delta-GlucopyranoseB-DextroseB-Glucoseb-δ-GlucopyranoseBeta-D-GlucopyranoseBeta-D-GlucoseBeta-delta-GlucopyranoseBeta-DextroseBeta-GlucoseD-glucoseD-Glucose-ringDextroseGlcGlc-ringGlucoseGlucosideβ-D-Glucopyranoseβ-D-Glucoseβ-Dextroseβ-Glucoseβ-δ-GlucopyranoseC6H12O6180.1559180.063388116(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrolglucoside492-61-5OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1WQZGKKKJIJFFOK-VFUOTHLCSA-NSolidCytoplasmPeriplasmlogp-2.57logs0.64solubility7.82e+02 g/llogp-2.9pka_strongest_acidic11.3pka_strongest_basic-3iupac(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrolaverage_mass180.1559mono_mass180.063388116smilesOC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OformulaC6H12O6inchiInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1inchikeyWQZGKKKJIJFFOK-VFUOTHLCSA-Npolar_surface_area110.38refractivity35.92polarizability16.35rotatable_bond_count1acceptor_count6donor_count5physiological_charge0formal_charge0Pentose phosphate pathwayec00030Starch and sucrose metabolismThe metabolism of starch and sucrose begins with D-fructose interacting with a D-glucose in a reversible reaction through a maltodextrin glucosidase resulting in a water molecule and a sucrose. D-fructose is phosphorylated through an ATP driven fructokinase resulting in the release of an ADP, a hydrogen ion and a Beta-D-fructofuranose 6-phosphate. This compound can also be introduced into the cytoplasm through either a mannose PTS permease or a hexose-6-phosphate:phosphate antiporter.
The Beta-D-fructofuranose 6-phosphate is isomerized through a phosphoglucose isomerase resulting in a Beta-D-glucose 6-phosphate. This compound can also be incorporated by glucose PTS permease or a hexose-6-phosphate:phosphate antiporter.
The beta-D-glucose 6 phosphate can also be produced by a D-glucose being phosphorylated by an ATP-driven glucokinase resulting in a ADP, a hydrogen ion and a Beta-D-glucose 6 phosphate.
The beta-D-glucose can produce alpha-D-glucose-1-phosphate by two methods:
1.-Beta-D-glucose is isomerized into an alpha-D-Glucose 6-phosphate and then interacts in a reversible reaction through a phosphoglucomutase-1 resulting in a alpha-D-glucose-1-phosphate.
2.-Beta-D-glucose interacts with a putative beta-phosphoglucomutase resulting in a Beta-D-glucose 1-phosphate. Beta-D-glucose 1-phosphate can be incorporated into the cytoplasm through a
glucose PTS permease. This compound is then isomerized into a Alpha-D-glucose-1-phosphate
The beta-D-glucose can cycle back into a D-fructose by first interacting with D-fructose in a reversible reaction through a Polypeptide: predicted glucosyltransferase resulting in the release of a phosphate and a sucrose. The sucrose then interacts in a reversible reaction with a water molecule through a maltodextrin glucosidase resulting in a D-glucose and a D-fructose.
Alpha-D-glucose-1-phosphate can produce glycogen in by two different sets of reactions:
1.-Alpha-D-glucose-1-phosphate interacts with a hydrogen ion and an ATP through a glucose-1-phosphate adenylyltransferase resulting in a pyrophosphate and an ADP-glucose. The ADP-glucose then interacts with an amylose through a glycogen synthase resulting in the release of an ADP and an Amylose. The amylose then interacts with 1,4-α-glucan branching enzyme resulting in glycogen
2.- Alpha-D-glucose-1-phosphate interacts with amylose through a maltodextrin phosphorylase resulting in a phosphate and a glycogen.
Alpha-D-glucose-1-phosphate can also interacts with UDP-galactose through a galactose-1-phosphate uridylyltransferase resulting in a galactose 1-phosphate and a Uridine diphosphate glucose. The UDP-glucose then interacts with an alpha-D-glucose 6-phosphate through a trehalose-6-phosphate synthase resulting in a uridine 5'-diphosphate, a hydrogen ion and a Trehalose 6- phosphate. The latter compound can also be incorporated into the cytoplasm through a trehalose PTS permease. Trehalose interacts with a water molecule through a trehalose-6-phosphate phosphatase resulting in the release of a phosphate and an alpha,alpha-trehalose.The alpha,alpha-trehalose can also be obtained from glycogen being metabolized through a glycogen debranching enzyme resulting in a the alpha, alpha-trehalose. This compound ca then be hydrated through a cytoplasmic trehalase resulting in the release of an alpha-D-glucose and a beta-d-glucose.
Glycogen is then metabolized by reacting with a phosphate through a glycogen phosphorylase resulting in a alpha-D-glucose-1-phosphate and a dextrin. The dextrin is then hydrated through a glycogen phosphorylase-limit dextrin α-1,6-glucohydrolase resulting in the release of a debranched limit dextrin and a maltotetraose. This compound can also be incorporated into the cytoplasm through a
maltose ABC transporter. The maltotetraose interacts with a phosphate through a maltodextrin phosphorylase releasing a alpha-D-glucose-1-phosphate and a maltotriose. The maltotriose can also be incorporated through a maltose ABC transporter. The maltotriose can then interact with water through a maltodextrin glucosidase resulting in a D-glucose and a D-maltose. D-maltose can also be incorporated through a
maltose ABC transporter
The D-maltose can then interact with a maltotriose through a amylomaltase resulting in a maltotetraose and a D-glucose. The D-glucose is then phosphorylated through an ATP driven glucokinase resulting in a hydrogen ion, an ADP and a Beta-D-glucose 6-phosphatePW000941ec00500MetabolicGlycolysis / Gluconeogenesisec00010Galactose metabolismGalactose can be synthesized through two pathways: melibiose degradation involving an alpha galactosidase and lactose degradation involving a beta galactosidase. Melibiose is first transported inside the cell through the melibiose:Li+/Na+/H+ symporter. Once inside the cell, melibiose is degraded through alpha galactosidase into an alpha-D-galactose and a beta-D-glucose. The beta-D-glucose is phosphorylated by a glucokinase to produce a beta-D-glucose-6-phosphate which can spontaneously be turned into a alpha D glucose 6 phosphate. This alpha D-glucose-6-phosphate is metabolized into a glucose -1-phosphate through a phosphoglucomutase-1. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase.
Galactose can also be produced by lactose degradation involving a lactose permease to uptake lactose from the environment and a beta-galactosidase to turn lactose into Beta-D-galactose.
Beta-D-galactose can also be uptaken from the environment through a galactose proton symporter.
Galactose is degraded through the following process:
Beta-D-galactose is introduced into the cytoplasm through a galactose proton symporter, or it can be synthesized from an alpha lactose that is introduced into the cytoplasm through a lactose permease. Alpha lactose interacts with water through a beta-galactosidase resulting in a beta-D-glucose and beta-D-galactose. Beta-D-galactose is isomerized into D-galactose. D-Galactose undergoes phosphorylation through a galactokinase, hence producing galactose 1 phosphate. On the other side of the pathway, a gluose-1-phosphate (product of the interaction of alpha-D-glucose 6-phosphate with a phosphoglucomutase resulting in a alpha-D-glucose-1-phosphate, an isomer of Glucose 1-phosphate, or an isomer of Beta-D-glucose 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine diphosphate glucose. This is followed by the interaction of galactose-1-phosphate with an established amount of uridine diphosphate glucose through a galactose-1-phosphate uridylyltransferase, which in turn output a glucose-1-phosphate and a uridine diphosphate galactose. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase, and so the cycle can keep going as long as more lactose or galactose is imported into the cell
PW000821ec00052MetabolicMicrobial metabolism in diverse environmentsec01120Metabolic pathwayseco01100Secondary metabolites: Trehalose Biosynthesis and MetabolismThrehalose biosynthesis begins with an Alpha-D-glucose-1-phosphate interacting with an ATP through a glucose-1-phosphate adenylyltransferase resulting in the release of a pyrophosphate and an ADP-glucose. The latter compound interacts in a reversible reaction with an amylose through a glycogen synthase resulting in the release of an ADP and an amylose. Amylose then interacts in a reversible reaction with 1,4-α-glucan branching enzyme resulting in a glycogen
Glycogen can also be produced by a reversible reaction with Amylose through a maltodextrin phosphorylase, releasing a phosphate and a glycogen.
Glycogen is then transformed into trehalose through a glycogen debranching enzyme.
Trehalose then interacts with a water molecule through a cytoplasmic trehalase resulting in the release of a Beta-D-glucose and an Alpha-D-glucose.
The beta-D-glucose is then phosphorylated by and ATP driven glucokinase resulting in a hydrogen ion, an ADP and a Beta-D-glucose 6-phosphate.PW000968Metaboliccolanic acid building blocks biosynthesisThe colonic acid building blocks biosynthesis starts with a Beta-D-Glucose undergoing a transport reaction mediated by a glucose PTS permease. The permease phosphorylates the Beta-D-Glucose, producing a Beta-D-Glucose 6-phosphate. This compound can either change to an Alpha-D-Glucose 6-phosphate spontaneously or into a fructose 6-phosphate through a glucose-6-phosphate isomerase. The latter compound can also be present in E.coli through the interaction of D-fructose and a mannose PTS permease which phosphorylate the D-fructose.
Fructose 6-phosphate interacts in a reversible reaction with mannose-6-phosphate isomerase in order to produce a Alpha-D-mannose 6-phosphate. This compound can also be present in E.coli through the interaction of Alpha-D-mannose and a mannose PTS permease which phosphorylates the alpha-D-mannose. Alpha-D-mannose 6-phosphate interacts in a reversible reaction with a phosphomannomutase to produce a alpha-D-mannose 1-phosphate. This compound in turn with a hydrogen ion and gtp undergoes a reaction with a mannose-1-phosphate guanylyltransferase, releasing a pyrophosphate and producing a guanosine diphosphate mannose. Guanosine diphosphate mannose interacts with gdp-mannose 4,6-dehydratase releasing a water, and gdp-4-dehydro-6-deoxy-D-mannose. This compound in turn with hydrogen ion and NADPH interact with GDP-L-fucose synthase releasing NADP and producing a GDP-L-fucose.
The Alpha-D-Glucose 6-phosphate interacts in a reversible reaction with phosphoglucomutase-1 to produce a alpha-D-glucose 1-phosphate. This in turn with UTP and hydrogen ion interact with UTP--glucose-1-phosphate uridyleltransferase releasing a pyrophosphate and UDP-glucose.
UDP-glucose can either interact with galactose-1-phosphate uridylyltransferase to produce a UDP-galactose or in turn with NAD and water interact with UDP-glucose 6-dehydrogenase releasing a NADH and a hydrogen ion and producing a UDP-glucuronate.
GDP-L-fucose, UDP-glucose, UDP-galactose and UDP-glucuronate are sugars that need to be activated in the form of nucleotide sugar prior to their assembly into colanic acid, also known as M antigen.
Colanic acid is an extracellular polysaccharide which has been linked to a cluster of 19 genes(wca).
PW000951Metabolicgalactose degradation/Leloir PathwayThe degradation of galactose, also known as Leloir pathway, requires 3 main enzymes once Beta-D-galactose has been converted to galactose through an Aldose-1-epimerase. These are: galactokinase , galactose-1-phosphate uridylyltransferase and UDP-glucose 4-epimerase. Beta-D-galactose can be uptaken from the environment through a galactose proton symporter. It can also be produced by lactose degradation involving a lactose permease to uptake lactose from the environment and a beta-galactosidase to turn lactose into Beta-D-galactose.
Galactose is degraded through the following process:
Beta-D-galactose is introduced into the cytoplasm through a galactose proton symporter, or it can be synthesized from an alpha lactose that is introduced into the cytoplasm through a lactose permease. Alpha lactose interacts with water through a beta-galactosidase resulting in a beta-D-glucose and beta-D-galactose. Beta-D-galactose is isomerized into D-galactose. D-Galactose undergoes phosphorylation through a galactokinase, hence producing galactose 1 phosphate. On the other side of the pathway, a gluose-1-phosphate (product of the interaction of alpha-D-glucose 6-phosphate with a phosphoglucomutase resulting in a alpha-D-glucose-1-phosphate, an isomer of Glucose 1-phosphate, or an isomer of Beta-D-glucose 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine diphosphate glucose. This is followed by the interaction of galactose-1-phosphate with an established amount of uridine diphosphate glucose through a galactose-1-phosphate uridylyltransferase, which in turn output a glucose-1-phosphate and a uridine diphosphate galactose. The glucose -1-phosphate is transformed into a uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine diphosphate glucose, can undergo a reversible reaction in which it can be turned into uridine diphosphategalactose through an UDP-glucose 4-epimerase, and so the cycle can keep going as long as more lactose or galactose is imported into the cell.
PW000884Metabolicmelibiose degradationPWY0-1301glycogen degradation IGLYCOCAT-PWYtrehalose degradation II (trehalase)PWY0-1182trehalose degradation VI (periplasmic)PWY0-1466glucose and glucose-1-phosphate degradationGLUCOSE1PMETAB-PWYlactose degradation IIIBGALACT-PWYtrehalose degradation I (low osmolarity)TREDEGLOW-PWYSpecdb::CMs3243Specdb::CMs30807Specdb::CMs30808Specdb::CMs37587Specdb::CMs99577Specdb::CMs99578Specdb::CMs136889Specdb::CMs144623Specdb::CMs1050439Specdb::CMs1050440Specdb::CMs1050442Specdb::CMs1050444Specdb::CMs1050446Specdb::CMs1050447Specdb::CMs1050449Specdb::CMs1050451Specdb::CMs1050453Specdb::CMs1050455Specdb::CMs1050457Specdb::CMs1050459Specdb::CMs1050460Specdb::CMs1050462Specdb::CMs1050464Specdb::CMs1050466Specdb::CMs1050468Specdb::EiMs1826Specdb::NmrOneD5259Specdb::NmrOneD5260Specdb::NmrOneD142310Specdb::NmrOneD142311Specdb::NmrOneD142312Specdb::NmrOneD142313Specdb::NmrOneD142314Specdb::NmrOneD142315Specdb::NmrOneD142316Specdb::NmrOneD142317Specdb::NmrOneD142318Specdb::NmrOneD142319Specdb::NmrOneD142320Specdb::NmrOneD142321Specdb::NmrOneD142322Specdb::NmrOneD142323Specdb::NmrOneD142324Specdb::NmrOneD142325Specdb::NmrOneD142326Specdb::NmrOneD142327Specdb::NmrOneD142328Specdb::NmrOneD142329Specdb::NmrOneD166522Specdb::NmrOneD166654Specdb::NmrOneD166667Specdb::MsMs1448592Specdb::MsMs1448593Specdb::MsMs1448594Specdb::MsMs1448595Specdb::MsMs1448596Specdb::MsMs1448597Specdb::MsMs1448598Specdb::MsMs1448599Specdb::MsMs1448600Specdb::MsMs1448601Specdb::MsMs1448602Specdb::MsMs1448603Specdb::MsMs1448604Specdb::MsMs1474236Specdb::MsMs1474237Specdb::MsMs1474238Specdb::MsMs1474239Specdb::MsMs1474240Specdb::MsMs1474241Specdb::MsMs1474242Specdb::MsMs1474243Specdb::MsMs1474244Specdb::MsMs1474245Specdb::MsMs1474246Specdb::MsMs1474247Specdb::NmrTwoD2074HMDB0051658238C00221GLCBGCKeseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590.21097882Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114.22080510van der Werf, M. J., Overkamp, K. M., Muilwijk, B., Coulier, L., Hankemeier, T. (2007). "Microbial metabolomics: toward a platform with full metabolome coverage." Anal Biochem 370:17-25.17765195Wenck, Helmut; Kinedt, Claudia; Bader, Hans Joachim. Production of b-D-glucose. Praxis der Naturwissenschaften, Chemie (1986), 35(4), 23. Beta-galactosidaseP00722BGAL_ECOLIlacZhttp://ecmdb.ca/proteins/P00722.xmlAlpha-galactosidaseP06720AGAL_ECOLImelAhttp://ecmdb.ca/proteins/P06720.xmlPTS system beta-glucoside-specific EIIBCA componentP08722PTV3B_ECOLIbglFhttp://ecmdb.ca/proteins/P08722.xmlGlucokinaseP0A6V8GLK_ECOLIglkhttp://ecmdb.ca/proteins/P0A6V8.xmlAldose 1-epimeraseP0A9C3GALM_ECOLIgalMhttp://ecmdb.ca/proteins/P0A9C3.xml6-phospho-beta-glucosidase BglBP11988BGLB_ECOLIbglBhttp://ecmdb.ca/proteins/P11988.xmlPeriplasmic trehalaseP13482TREA_ECOLItreAhttp://ecmdb.ca/proteins/P13482.xmlQuinoprotein glucose dehydrogenaseP15877DHG_ECOLIgcdhttp://ecmdb.ca/proteins/P15877.xml4-alpha-glucanotransferaseP15977MALQ_ECOLImalQhttp://ecmdb.ca/proteins/P15977.xml6-phospho-beta-glucosidaseP17411CHBF_ECOLIchbFhttp://ecmdb.ca/proteins/P17411.xmlPTS system maltose- and glucose-specific EIICB componentP19642PTOCB_ECOLImalXhttp://ecmdb.ca/proteins/P19642.xml6-phospho-beta-glucosidase AscBP24240ASCB_ECOLIascBhttp://ecmdb.ca/proteins/P24240.xmlTrehalose-6-phosphate hydrolaseP28904TREC_ECOLItreChttp://ecmdb.ca/proteins/P28904.xmlPeriplasmic beta-glucosidaseP33363BGLX_ECOLIbglXhttp://ecmdb.ca/proteins/P33363.xmlCytoplasmic trehalaseP62601TREF_ECOLItreFhttp://ecmdb.ca/proteins/P62601.xmlGlucose-specific phosphotransferase enzyme IIA componentP69783PTGA_ECOLIcrrhttp://ecmdb.ca/proteins/P69783.xmlPTS system glucose-specific EIICB componentP69786PTGCB_ECOLIptsGhttp://ecmdb.ca/proteins/P69786.xml6-phospho-beta-glucosidase BglAQ46829BGLA_ECOLIbglAhttp://ecmdb.ca/proteins/Q46829.xmlBeta-galactosidaseG0ZKW2G0ZKW2_ECOLIlacZhttp://ecmdb.ca/proteins/G0ZKW2.xmlPTS system beta-glucoside-specific EIIBCA componentP08722PTV3B_ECOLIbglFhttp://ecmdb.ca/proteins/P08722.xmlPTS system maltose- and glucose-specific EIICB componentP19642PTOCB_ECOLImalXhttp://ecmdb.ca/proteins/P19642.xmlPTS system glucose-specific EIICB componentP69786PTGCB_ECOLIptsGhttp://ecmdb.ca/proteins/P69786.xmlSugar efflux transporter CP31436SETC_ECOLIsetChttp://ecmdb.ca/proteins/P31436.xmlCellobiose + Water <>2 b-D-GlucoseR00026Adenosine triphosphate + b-D-Glucose <> ADP + beta-D-Glucose 6-phosphateR01600alpha-D-Glucose <> b-D-GlucoseR01602Cellulose + Water <> Cellulose + b-D-GlucoseR028873-Ketolactose + Water <> 3-Keto-beta-D-galactose + b-D-GlucoseR04783b-D-Glucose <> D-glucoseRXN0-6418Phosphoenolpyruvic acid + b-D-Glucose > Glucose 6-phosphate + Pyruvic acidTRANS-RXN-157a β-D glucoside + Water a non glucosylated glucose acceptor + b-D-Glucose3.2.1.21-RXNCellobiose-6-phosphate + Water > Glucose 6-phosphate + b-D-Glucose6-PHOSPHO-BETA-GLUCOSIDASE-RXND-Glucose <> b-D-GlucoseALDOSE-1-EPIMERASE-RXNWater + Melibiose > D-Galactose + b-D-GlucoseALPHAGALACTOSID-RXNMaltotriose + D-Maltose <> Maltotetraose + b-D-GlucoseAMYLOMALT-RXNWater + alpha-Lactose > D-Galactose + b-D-GlucoseBETAGALACTOSID-RXNGDP-α-D-glucose + Water > Hydrogen ion + b-D-Glucose + Guanosine diphosphateGDP-GLUCOSIDASE-RXNb-D-Glucose + a ubiquinone > Gluconolactone + a ubiquinolGLUCDEHYDROG-RXNb-D-Glucose + Adenosine triphosphate > Hydrogen ion + Glucose 6-phosphate + ADPGLUCOKIN-RXNisoprimeverose + Water b-D-Glucose + D-XyloseRXN-12402Gluconolactone + Hydrogen ion <> b-D-GlucoseRXN0-6372Trehalose 6-phosphate + Water > Glucose 6-phosphate + b-D-GlucoseTRE6PHYDRO-RXNTrehalose + Water > b-D-Glucose + D-GlucoseTREHALA-RXNalpha-D-Glucose > b-D-GlucoseR01602Trehalose + Water > b-D-Glucose + alpha-D-GlucoseTrehalose + Water <> b-D-Glucose + alpha-D-GlucoseR00010 R06103 alpha-Lactose + Water > beta-D-Galactose + Beta-D-Glucose + b-D-GlucosePW_R002956Beta-D-Glucose + Adenosine triphosphate + b-D-Glucose > Hydrogen ion + Adenosine diphosphate + beta-D-Glucose 6-phosphate + ADPPW_R003297Melibiose + Water > Alpha-D-Galactose + Beta-D-Glucose + b-D-GlucosePW_R003298α,α-trehalose + Water > alpha-D-Glucose + Beta-D-Glucose + b-D-GlucosePW_R003516Beta-D-Glucose + HPr - phosphorylated + b-D-Glucose > beta-D-Glucose 6-phosphate + HPrPW_RCT000138Cellobiose + Water <>2 b-D-GlucoseAdenosine triphosphate + b-D-Glucose <> ADP + beta-D-Glucose 6-phosphateAdenosine triphosphate + b-D-Glucose <> ADP + beta-D-Glucose 6-phosphate