Identification
Name:DNA mismatch repair protein MutH
Synonyms:Not Available
Gene Name:mutH
Enzyme Class:Not Available
Biological Properties
General Function:regulation of DNA recombination
Specific Function:Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
DNA binding
DNA modification
endonuclease activity
mismatch repair
mismatch repair complex
nucleic acid phosphodiester bond hydrolysis
regulation of DNA recombination
T/G mismatch-specific endonuclease activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>690
atgtcccaacctcgcccactgctctctcctcccgaaactgaagaacagttgttagcgcaa
gcacagcaactttctggttatacattgggagaactggcggcacttgtcgggctggttacg
ccagagaatttaaaacgcgataaaggctggattggcgtgttactggagatctggctaggt
gccagcgcagggagtaaacctgagcaagattttgctgctctgggcgtggaacttaaaact
atccctgtggatagtcttggtcgtccgctggaaacaacattcgtttgtgttgccccgtta
acgggcaatagcggggtgacctgggaaaccagccacgtgcgccacaaactcaaacgcgta
ctgtggataccggttgaaggcgagcgcagcatcccgctggcgcagcgtcgcgttggatca
ccgttgctgtggagcccgaatgaagaggaagaccggcagctacgcgaagactgggaagaa
ttaatggatatgattgttctcggtcaggttgagcggattaccgctcgtcacggggagtat
ttacagatacgaccgaaagcagcgaatgcgaaagcgcttaccgaagccattggtgcccgg
ggcgaacggattctgacgctgccacgcggcttttatttgaagaagaatttcaccagtgca
ctactggcccgtcattttctgatccagtag
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:229
Protein Molecular Weight:25527
Protein Theoretical pI:Not Available
PDB File:1AZO
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>DNA mismatch repair protein MutH
MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALVGLVTPENLKRDKGWIGVLLEIWLG
ASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRV
LWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEELMDMIVLGQVERITARHGEY
LQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFTSALLARHFLIQ
References
External Links:
ResourceLink
Uniprot ID:P06722
Uniprot Name:MUTH_ECOLI
PDB ID:1AZO
CCDB:MUTH_ECOLI
General Reference:Not Available