Identification
Name:Methyl-accepting chemotaxis protein II
Synonyms:Not Available
Gene Name:tar
Enzyme Class:Not Available
Biological Properties
General Function:chemotaxis
Specific Function:Receptor for the attractant L-aspartate and related amino and dicarboxylic acids. Tar also mediates taxis to the attractant maltose via an interaction with the periplasmic maltose binding protein. Tar mediates taxis away from the repellents cobalt and nickel.Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
chemotaxis
integral component of plasma membrane
protein histidine kinase binding
signal transducer activity
transmembrane signaling receptor activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1662
atgattaaccgtatccgcgtagtcacgctgttggtaatggtgctgggggtattcgcactg
ttacagcttatttccggcagtctgtttttttcttcccttcaccatagccagaagagcttt
gtggtttccaatcaattacgggaacagcagggcgagctgacgtcaacctgggatttaatg
ctgcaaacgcgcattaacctgagtcgttcagcggtacggatgatgatggattcctccaat
caacaaagtaacgccaaagttgaattgctcgatagcgccaggaaaacattggcgcaggca
gcgacgcattataaaaaattcaaaagcatggcaccgttacctgaaatggtcgctaccagt
cgtaatattgatgaaaaatataaaaactattacacagcgttaactgaactgattgattat
ctagattatggcaatactggagcttatttcgctcagccaacccagggaatgcaaaatgca
atgggcgaagcgtttgctcagtacgccctcagcagtgaaaaactgtatcgcgatatcgtc
actgacaacgcagatgattaccgatttgcccagtggcaactggcggttatcgcgctggtg
gtggtattgattctgctggtggcgtggtacggcattcgccgtatgttgcttactccgctg
gcaaaaattattgctcacattcgcgaaatcgccggtggtaacctggcgaataccctgacc
attgacgggcgcagtgaaatgggcgacctggcgcagagcgtttcacatatgcaacgctct
ttgactgacaccgtcactcatgtccgcgaaggttcagatgccatctatgccggtacccgt
gaaattgcggcgggcaacaccgatctttcctcccgtactgaacagcaggcatccgcgctg
gaagaaactgccgccagcatggagcagctcaccgcgacagtgaagcaaaacgccgataac
gcccgccaggcctcgcaactggcgcaaagtgcctccgacaccgcccagcacggcggcaaa
gtggtggatggcgtagtgaaaacgatgcatgagatcgccgatagttcgaagaaaattgcc
gacattatcagcgttatcgacggtattgccttccagactaatatcctcgcgctgaatgcc
gcggttgaagccgcgcgtgcgggtgaacagggccgtggttttgccgtggtggcgggtgaa
gtgcgtaatcttgccagtcgcagcgcccaggcggcaaaagagatcaaagccctcattgaa
gactccgtctcacgcgttgataccggttcggtgctggtcgaaagcgccggggaaacaatg
aacaatatcgtcaatgctgtcactcgcgtgactgacattatgggcgagattgcatcggca
tcggatgaacagagccgtggcatcgatcaagtcgcattggcggtttcggaaatggatcgc
gtcacgcaacagaacgcatcgctggtgcaggaatcagctgccgccgccgctgcgctggaa
gaacaggcgagtcgtttaacgcaagcagtttccgcgttccgtctggcagccagcccactc
accaataaaccgcaaacaccatcccgtcctgccagtgagcaaccaccggctcagccacga
ctgcgaattgctgaacaagatccaaactgggaaacattttga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:553
Protein Molecular Weight:59943
Protein Theoretical pI:Not Available
PDB File:2ASR
Signaling Regions:Not Available
Transmembrane Regions:
  • 7-33
  • 191-211
Protein Sequence:
>Methyl-accepting chemotaxis protein II
MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLM
LQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATS
RNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIV
TDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLT
IDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASAL
EETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIA
DIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIE
DSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDR
VTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAASPLTNKPQTPSRPASEQPPAQPR
LRIAEQDPNWETF
References
External Links:
ResourceLink
Uniprot ID:P07017
Uniprot Name:MCP2_ECOLI
PDB ID:2ASR
CCDB:MCP2_ECOLI
General Reference:Not Available