Identification
Name:Protein FimH
Synonyms:Not Available
Gene Name:fimH
Enzyme Class:Not Available
Biological Properties
General Function:cell adhesion
Specific Function:Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell adhesion
mannose binding
pilus
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>903
atgaaacgagttattaccctgtttgctgtactgctgatgggctggtcggtaaatgcctgg
tcattcgcctgtaaaaccgccaatggtaccgctatccctattggcggtggcagcgccaat
gtttatgtaaaccttgcgcccgtcgtgaatgtggggcaaaacctggtcgtggatctttcg
acgcaaatcttttgccataacgattatccggaaaccattacagactatgtcacactgcaa
cgaggctcggcttatggcggcgtgttatctaatttttccgggaccgtaaaatatagtggc
agtagctatccatttcctaccaccagcgaaacgccgcgcgttgtttataattcgagaacg
gataagccgtggccggtggcgctttatttgacgcctgtgagcagtgcgggcggggtggcg
attaaagctggctcattaattgccgtgcttattttgcgacagaccaacaactataacagc
gatgatttccagtttgtgtggaatatttacgccaataatgatgtggtggtgcctactggc
ggctgcgatgtttctgctcgtgatgtcaccgttactctgccggactaccctggttcagtg
ccaattcctcttaccgtttattgtgcgaaaagccaaaacctggggtattacctctccggc
acaaccgcagatgcgggcaactcgattttcaccaataccgcgtcgttttcacctgcacag
ggcgtcggcgtacagttgacgcgcaacggtacgattattccagcgaataacacggtatcg
ttaggagcagtagggacttcggcggtgagtctgggattaacggcaaattatgcacgtacc
ggagggcaggtgactgcagggaatgtgcaatcgattattggcgtgacttttgtttatcaa
taa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:300
Protein Molecular Weight:31473
Protein Theoretical pI:Not Available
PDB File:1KIU
Signaling Regions:
  • 1-21
Transmembrane Regions:Not Available
Protein Sequence:
>Protein FimH
MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLS
TQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRT
DKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPTG
GCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGTTADAGNSIFTNTASFSPAQ
GVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTANYARTGGQVTAGNVQSIIGVTFVYQ
References
External Links:
ResourceLink
Uniprot ID:P08191
Uniprot Name:FIMH_ECOLI
PDB ID:1KIU
CCDB:FIMH_ECOLI
General Reference:Not Available