Identification
Name:Arginine repressor
Synonyms:Not Available
Gene Name:argR
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Negatively controls the expression of the four operons of arginine biosynthesis in addition to the carAB operon. Predominantly interacts with A/T residues in ARG boxes. It also binds to a specific site in cer locus. Thus it is essential for cer-mediated site-specific recombination in ColE1. It is necessary for monomerization of the plasmid ColE1.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
arginine binding
arginine biosynthetic process
cytoplasm
negative regulation of DNA-templated transcription, initiation
plasmid recombination
protein oligomerization
sequence-specific DNA binding transcription factor activity
transcription regulatory region DNA binding
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>471
atgcgaagctcggctaagcaagaagaactagttaaagcatttaaagcattacttaaagaa
gagaaatttagctcccagggcgaaatcgtcgccgcgttgcaggagcaaggctttgacaat
attaatcagtctaaagtctcgcggatgttgaccaagtttggtgctgtacgtacacgcaat
gccaaaatggaaatggtttactgcctgccagctgaactgggtgtaccaaccacctccagt
ccattgaagaatctggtgctggatatcgactacaacgatgcagttgtcgtgattcatacc
agccctggcgcggcgcagttaattgctcgcctgctggactcactgggcaaagcagaaggt
attctgggcaccatcgctggcgatgacaccatctttaccacccctgctaacggtttcaca
gtcaaagacctgtacgaagcgattttagagctgttcgaccaggagctttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:156
Protein Molecular Weight:16994
Protein Theoretical pI:Not Available
PDB File:1AOY
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Arginine repressor
MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRN
AKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEG
ILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL
References
External Links:
ResourceLink
Uniprot ID:P0A6D0
Uniprot Name:ARGR_ECOLI
PDB ID:1AOY
CCDB:ARGR_ECOLI
General Reference:Not Available