| Identification |
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| Name: | ATP-dependent Clp protease ATP-binding subunit ClpX |
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| Synonyms: | Not Available |
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| Gene Name: | clpX |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | viral process |
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| Specific Function: | ATP-dependent specificity component of the Clp protease. Uses cycles of ATP binding and hydrolysis to unfold proteins and translocate them to the ClpP protease. It directs the protease to specific substrates both with and without the help of adapter proteins such as SspB. Participates in the final steps of RseA-sigma-E degradation, liberating sigma-E to induce the extracytoplasmic-stress response. It may bind to the lambda O substrate protein and present it to the ClpP protease in a form that can be recognized and readily hydrolyzed by ClpP. Can perform chaperone functions in the absence of ClpP. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| ATP binding | | ATP-dependent peptidase activity | | ATPase activity | | cell division | | identical protein binding | | protein folding | | protein unfolding | | proteolysis | | viral process | | zinc ion binding |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1275
atgacagataaacgcaaagatggctcaggcaaattgctgtattgctctttttgcggcaaa
agccagcatgaagtgcgcaagctgattgccggtccatccgtgtatatctgcgacgaatgt
gttgatttatgtaacgacatcattcgcgaagagattaaagaagttgcaccgcatcgtgaa
cgcagtgcgctaccgacgccgcatgaaattcgcaaccacctggacgattacgttatcggc
caggaacaggcgaaaaaagtgctggcggtcgcggtatacaaccattacaaacgtctgcgc
aacggcgataccagcaatggcgtcgagttgggcaaaagtaacattctgctgatcggtccg
accggttccggtaaaacgctgctggctgaaacgctggcgcgcctgctggatgttccgttc
accatggccgacgcgactacactgaccgaagccggttatgtgggtgaagacgttgaaaac
atcattcagaagctgttgcagaaatgcgactacgatgtccagaaagcacagcgtggtatt
gtctacatcgatgaaatcgacaagatttctcgtaagtcagacaacccgtccattacccga
gacgtttccggtgaaggcgtacagcaggcactgttgaaactgatcgaaggtacggtagct
gctgttccaccgcaaggtgggcgtaaacatccgcagcaggaattcttgcaggttgatacc
tctaagatcctgtttatttgtggcggtgcgtttgccggtctggataaagtgatttcccac
cgtgtagaaaccggctccggcattggttttggcgcgacggtaaaagcgaagtccgacaaa
gcaagcgaaggcgagctgctggcgcaggttgaaccggaagatctgatcaagtttggtctt
atccctgagtttattggtcgtctgccggttgtcgcaacgttgaatgaactgagcgaagaa
gctctgattcagatcctcaaagagccgaaaaacgccctgaccaagcagtatcaggcgctg
tttaatctggaaggcgtggatctggaattccgtgacgaggcgctggatgctatcgctaag
aaagcgatggcgcgtaaaaccggtgcccgtggcctgcgttccatcgtagaagccgcactg
ctcgataccatgtacgatctgccgtccatggaagacgtcgaaaaagtggttatcgacgag
tcggtaattgatggtcaaagcaaaccgttgctgatttatggcaagccggaagcgcaacag
gcatctggtgaataa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 424 |
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| Protein Molecular Weight: | 46355 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1OVX |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >ATP-dependent Clp protease ATP-binding subunit ClpX
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRE
RSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGP
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGL
IPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAK
KAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIDGQSKPLLIYGKPEAQQ
ASGE |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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