(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase (P0A6Q6)

• (3R)-hydroxymyristoyl ACP dehydrase
• 17 kDa actomyosin component

• 4.2.1.59

• Biotin metabolism PW000762
• Fatty acid biosynthesis PW000900
• Fatty acid metabolism PW000796
• fatty acid elongation -- saturated PW000798
• palmitate biosynthesis PW000797
• palmitate biosynthesis 2 PW002044

• Biotin metabolism ec00780
• Fatty acid biosynthesis ec00061
• Fatty acid metabolism ec00071
• Metabolic pathways eco01100

>456 bp
TTGACTACTAACACTCATACTCTGCAGATTGAAGAGATTTTAGAACTTCTGCCGCACCGT
TTCCCGTTCTTACTGGTGGATCGCGTGCTGGATTTTGAAGAAGGTCGTTTTCTGCGCGCA
GTAAAAAATGTCTCTGTCAATGAGCCATTCTTCCAGGGCCATTTCCCTGGAAAACCGATT
TTCCCGGGTGTGCTGATTCTGGAAGCAATGGCACAGGCAACAGGTATTCTGGCGTTTAAA
AGCGTAGGAAAACTGGAACCGGGTGAGCTGTACTACTTCGCTGGTATTGACGAAGCGCGC
TTCAAGCGCCCGGTCGTGCCTGGCGATCAAATGATCATGGAAGTCACTTTCGAAAAAACG
CGCCGCGGCCTGACCCGTTTTAAAGGGGTTGCTCTGGTCGATGGTAAAGTAGTTTGCGAA
GCAACGATGATGTGTGCTCGTAGCCGGGAGGCCTGA

• FabA (PF07977 )

• None

• None

>(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPI
FPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKT
RRGLTRFKGVALVDGKVVCEATMMCARSREA

• Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
• Coleman, J., Raetz, C. R. (1988). "First committed step of lipid A biosynthesis in Escherichia coli: sequence of the lpxA gene." J Bacteriol 170:1268-1274. Pubmed: 3277952
• Foster, S. J. (1993). "Purification and characterization of an 'actomyosin' complex from Escherichia coli W3110." FEMS Microbiol Lett 110:295-298. Pubmed: 8354462
• Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
• Mohan, S., Kelly, T. M., Eveland, S. S., Raetz, C. R., Anderson, M. S. (1994). "An Escherichia coli gene (FabZ) encoding (3R)-hydroxymyristoyl acyl carrier protein dehydrase. Relation to fabA and suppression of mutations in lipid A biosynthesis." J Biol Chem 269:32896-32903. Pubmed: 7806516
• Ogura, T., Inoue, K., Tatsuta, T., Suzaki, T., Karata, K., Young, K., Su, L. H., Fierke, C. A., Jackman, J. E., Raetz, C. R., Coleman, J., Tomoyasu, T., Matsuzawa, H. (1999). "Balanced biosynthesis of major membrane components through regulated degradation of the committed enzyme of lipid A biosynthesis by the AAA protease FtsH (HflB) in Escherichia coli." Mol Microbiol 31:833-844. Pubmed: 10048027