Ribosomal RNA small subunit methyltransferase G (P0A6U5)

Identification
Name:Ribosomal RNA small subunit methyltransferase G
Synonyms:
  • 16S rRNA 7-methylguanosine methyltransferase
  • 16S rRNA m7G methyltransferase
  • Glucose-inhibited division protein B
Gene Name:rsmG
Enzyme Class:
Biological Properties
General Function:Cell wall/membrane/envelope biogenesis
Specific Function:Specifically methylates the N7 position of guanosine in position 527 of 16S rRNA
Cellular Location:Cytoplasm (Potential)
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
ECMDB00939S-AdenosylhomocysteineMetaboCard
GO Classification:
Component
cell part
cytoplasm
intracellular part
Function
catalytic activity
methyltransferase activity
RNA methyltransferase activity
rRNA methyltransferase activity
transferase activity
transferase activity, transferring one-carbon groups
Process
cellular macromolecule metabolic process
macromolecule metabolic process
metabolic process
ncRNA metabolic process
RNA metabolic process
rRNA metabolic process
rRNA processing
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>624 bp
ATGGCTCAAGGCACGCTTTATATTGTTTCTGCCCCCAGTGGCGCGGGTAAATCCAGCCTG
ATTCAGGCTTTATTAAAAACCCAACCGTTGTATGACACCCAGGTTTCTGTTTCACACACC
ACACGCCAACCGCGTCCTGGTGAAGTCCACGGTGAACATTATTTCTTTGTTAATCATGAT
GAATTTAAAGAAATGATTAGCAGAGATGCGTTCCTCGAACACGCAGAAGTTTTTGGTAAT
TACTATGGCACTTCGCGTGAGGCCATTGAGCAAGTACTGGCGACCGGTGTCGATGTTTTT
CTCGATATCGACTGGCAGGGCGCGCAGCAAATTCGCCAGAAGATGCCGCACGCGCGGAGT
ATCTTTATTTTACCGCCGTCCAAAATTGAACTGGACCGCCGTCTACGCGGTCGCGGTCAG
GACAGCGAAGAGGTCATTGCAAAGCGTATGGCGCAAGCTGTTGCAGAAATGAGCCATTAC
GCCGAATATGATTATCTGATTGTGAATGATGACTTCGATACCGCGTTGACCGATTTGAAG
ACCATTATTCGCGCCGAACGTCTGCGCATGAGCCGCCAAAAGCAGCGTCATGACGCTTTA
ATCAGCAAATTGTTGGCAGACTGA
Protein Properties
Pfam Domain Function:
Protein Residues:207
Protein Molecular Weight:23431
Protein Theoretical pI:7
PDB File:1JSX
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Ribosomal RNA small subunit methyltransferase G
MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVRDPNEMLVRHILDSIVV
APYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRVRFLRQVQHELKLENIEPV
QSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGRFYALKGQMPEDEIALLPEEY
QVESVVKLQVPALDGERHLVVIKANKI
References
External Links:
ResourceLink
Uniprot ID:P0A6U5
Uniprot Name:RSMG_ECOLI
GenBank Gene ID:L10328
Genebank Protein ID:290498
PDB ID:1JSX
CCDB:RSMG_ECOLI
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Burland, V., Plunkett, G. 3rd, Daniels, D. L., Blattner, F. R. (1993). "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication." Genomics 16:551-561. Pubmed: 7686882
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Nielsen, J., Jorgensen, B. B., van Meyenburg, K. V., Hansen, F. G. (1984). "The promoters of the atp operon of Escherichia coli K12." Mol Gen Genet 193:64-71. Pubmed: 6318052
  • Okamoto, S., Tamaru, A., Nakajima, C., Nishimura, K., Tanaka, Y., Tokuyama, S., Suzuki, Y., Ochi, K. (2007). "Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria." Mol Microbiol 63:1096-1106. Pubmed: 17238915
  • Romanowski, M. J., Bonanno, J. B., Burley, S. K. (2002). "Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold." Proteins 47:563-567. Pubmed: 12001236
  • Walker, J. E., Gay, N. J., Saraste, M., Eberle, A. N. (1984). "DNA sequence around the Escherichia coli unc operon. Completion of the sequence of a 17 kilobase segment containing asnA, oriC, unc, glmS and phoS." Biochem J 224:799-815. Pubmed: 6395859