Identification |
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Name: | Transcription elongation factor GreA |
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Synonyms: | Not Available |
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Gene Name: | greA |
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Enzyme Class: | Not Available |
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Biological Properties |
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General Function: | regulation of DNA-templated transcription, elongation |
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Specific Function: | Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. |
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Cellular Location: | Not Available |
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SMPDB Pathways: | Not Available |
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KEGG Pathways: | Not Available |
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Metabolites: | |
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GO Classification: | Function |
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bacterial-type RNA polymerase holo enzyme binding | cytoplasm | DNA binding | DNA-templated transcription, elongation | regulation of DNA-templated transcription, elongation |
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Gene Properties |
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Blattner: | Not Available |
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Gene Orientation | Not Available |
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Centisome Percentage: | Not Available |
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Left Sequence End | Not Available |
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Right Sequence End | Not Available |
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Gene Sequence: | >477
atgcaagctattccgatgaccttacgcggcgctgaaaaattacgcgaagagctggatttt
ctgaaatctgtgcgccgtcctgaaatcattgctgctatcgcggaagcgcgtgagcatggc
gacctgaaagaaaacgccgaataccacgcagctcgtgaacagcagggtttctgcgaaggc
cgtattaaagacatcgaagccaagctgtcgaacgcgcaggtgattgatgtcaccaaaatg
cccaacaatgggcgcgttatttttggtgctaccgtaacggtgctgaatctggattctgac
gaagaacagacttatcgcatcgttggcgatgacgaagctgactttaaacaaaacctgatt
tctgtaaactcgcctattgctcgtggcctgatcggcaaagaagaagatgatgttgtggtc
atcaaaacgccgggcggcgaagtagaatttgaagtaattaaggtggaatacctgtaa |
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Protein Properties |
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Pfam Domain Function: | Not Available |
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Protein Residues: | 158 |
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Protein Molecular Weight: | 17640 |
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Protein Theoretical pI: | Not Available |
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PDB File: | 1GRJ |
Signaling Regions: | Not Available |
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Transmembrane Regions: | Not Available |
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Protein Sequence: | >Transcription elongation factor GreA
MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKENAEYHAAREQQGFCEG
RIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEEQTYRIVGDDEADFKQNLI
SVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL |
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References |
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External Links: | |
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General Reference: | Not Available |
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