ECMDB: Nickel-responsive regulator (P0A6Z6)

Identification

Name:

Nickel-responsive regulator

Synonyms:

Not Available

Gene Name:

nikR

Enzyme Class:

Not Available

Biological Properties

General Function:

transcription, DNA-templated

Specific Function:

Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
DNA binding
nickel cation binding
protein-DNA complex
regulation of transcription, DNA-templated
response to nickel cation
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>402
atgcaacgagtcaccatcacgcttgatgacgatttactggagacgctggacagcctgagc
cagcgtcgtggttataacaaccgttccgaagctatccgcgacattctgcgtagcgccctg
gcgcaagaggccacccagcagcacggcacgcaaggtttcgcggtgctgtcgtatgtgtat
gaacacgaaaaacgcgacttagccagccgcattgtctccacccagcatcatcaccacgac
ctctccgtcgccacgctgcatgtgcacatcaaccacgacgactgtctggaaatcgccgtg
ttgaaaggtgacatgggtgacgtgcagcattttgccgatgacgttatcgcccagcgcggc
gtgcggcacgggcatttgcagtgcttgccgaaggaagattga

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

133

Protein Molecular Weight:

15093

Protein Theoretical pI:

Not Available

PDB File:

1Q5V

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Nickel-responsive regulator
MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVY
EHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRG
VRHGHLQCLPKED

References

External Links:

Resource	Link
Uniprot ID:	P0A6Z6
Uniprot Name:	NIKR_ECOLI
PDB ID:	1Q5V
CCDB:	NIKR_ECOLI

General Reference:

Not Available