| Identification |
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| Name: | Translation initiation factor IF-2 |
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| Synonyms: | Not Available |
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| Gene Name: | infB |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | translational initiation |
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| Specific Function: | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| cytoplasm | | GTP binding | | GTPase activity | | guanosine tetraphosphate binding | | membrane | | ribosomal small subunit binding | | translation initiation factor activity | | translational initiation |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >2673
atgacagatgtaacgattaaaacgctggccgcagagcgacagacctccgtggaacgcctg
gtacagcaatttgctgatgcaggtatccggaagtctgctgacgactctgtgtctgcacaa
gagaaacagactttgattgaccacctgaatcagaaaaattcaggcccggacaaattgacg
ctgcaacgtaaaacacgcagcacccttaacattcctggtaccggtggaaaaagcaaatcg
gtacaaatcgaagtccgcaagaaacgcacctttgtgaaacgcgatccgcaagaggctgaa
cgccttgcagcggaagagcaagcgcagcgtgaagcggaagagcaagcccgtcgtgaggca
gaagaatcggctaaacgcgaggcgcaacaaaaagctgaacgtgaggccgcagaacaagct
aagcgtgaagctgctgaacaagcgaaacgtgaagctgcggaaaaagacaaagtgagcaat
caacaagacgatatgactaaaaacgcccaggctgaaaaagcccgccgtgagcaggaagct
gcagagctcaagcgtaaagctgaagaagaagcgcgtcgtaaactcgaagaagaagcacgt
cgcgttgctgaagaagcacgtcgtatggcggaagaaaacaaatggactgataacgcggaa
ccgactgaagattccagcgattatcacgtcactacttctcaacatgctcgccaggcagaa
gacgaaagcgatcgtgaagtcgaaggcggccgtggccgtggtcgtaacgcgaaagcagcg
cgtccgaagaaaggcaacaaacacgctgaatcaaaagctgatcgtgaagaagcacgcgca
gcagtacgtggcggtaaaggcggaaaacgtaaaggttcttcgctgcagcaaggcttccag
aagcctgctcaggccgttaaccgtgacgttgtgatcggcgaaactatcaccgttggcgaa
ctggcgaacaagatggcggttaaaggctctcaggtcatcaaagcgatgatgaaactgggc
gcaatggcaaccatcaaccaggttatcgatcaggaaaccgcacagctggttgctgaagag
atgggccataaagttatcctgcgtcgtgaaaacgagctggaagaggcggtaatgagcgac
cgtgacacgggtgctgcggctgaaccgcgcgcgccggttgtgaccatcatgggtcacgtt
gaccacggtaaaacctctctgctggactacattcgttcaacgaaagtggcctctggcgaa
gcgggcggcattacccagcacattggtgcataccacgttgaaactgaaaacggcatgatc
accttcctggacaccccggggcacgccgcgtttacttcaatgcgtgctcgtggtgcgcag
gcaacggacatcgtagtcctggttgttgctgccgacgacggtgtgatgccgcagaccatc
gaagcaatccagcacgcgaaagcggcgcaggtaccggtggtggttgcagtgaacaagatc
gataaaccagaagctgatccggatcgcgttaagaacgaactctcccagtacggcatcctg
ccggaagagtggggcggtgaaagccagttcgtacacgtatctgcgaaagcgggtaccggt
atcgatgaactgctggacgctatcctgctgcaggcggaagttctggagctgaaagcggta
cgtaaaggtatggcgagcggtgcggttatcgaatccttcctcgataaaggtcgtggtccg
gttgctaccgttctggtacgtgaaggtactctgcacaagggcgatatcgttctgtgtggc
ttcgaatacggtcgtgttcgtgcgatgcgtaacgaactgggtcaggaagtgctggaagcg
ggtccgtccattccggtggaaatcctcggcctgtccggcgtaccggctgcgggtgatgaa
gttaccgttgtacgtgacgagaagaaagcgcgtgaagttgcactctatcgtcagggtaaa
ttccgcgaagttaaactggcgcgtcagcagaaatctaaactcgagaacatgttcgccaac
atgaccgaaggcgaagttcacgaagtgaatatcgtcctgaaggcagacgtacagggttct
gtcgaagcgatctccgactccttgctgaaactgtctactgacgaagttaaagtgaagatc
atcggttctggcgtaggtggtatcaccgaaaccgacgccaccctggctgcggcgtccaac
gccatcctggttggctttaacgtacgtgctgatgcctctgcacgtaaagtgattgaagcg
gaaagcctggatctgcgttactactccgtcatctataacctgattgacgaagtgaaagcg
gcgatgagcggtatgctgtctccggaactgaaacagcagattatcggtctggcggaagtt
cgtgacgtgttcaaatcgccgaaatttggtgccatcgcaggctgtatggttaccgaaggt
gtggttaaacgtcacaacccgatccgcgttctgcgtgacaacgtggttatctacgaaggc
gagctggagtccctgcgccgcttcaaagatgacgttaacgaagtccgtaacggtatggaa
tgtggtatcggcgttaagaactacaacgacgtccgcactggcgatgtgatcgaagtattc
gaaatcatcgagatccaacgtaccattgcttaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 890 |
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| Protein Molecular Weight: | 97349 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1ND9 |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Translation initiation factor IF-2
MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLT
LQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREA
EESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEA
AELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAE
DESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQ
KPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEE
MGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGE
AGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTI
EAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTG
IDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCG
FEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGK
FREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKI
IGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKA
AMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEG
ELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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