Identification
Name:Ribosome-binding factor A
Synonyms:Not Available
Gene Name:rbfA
Enzyme Class:Not Available
Biological Properties
General Function:response to cold
Specific Function:Essential for efficient processing of 16S rRNA. Probably part of the 30S subunit prior to or during the final step in the processing of 16S free 30S ribosomal subunits. Could be some accessory protein needed for efficient assembly of the 30S subunit. May interact with the 5'-terminal helix region of 16S rRNA. Has affinity for free ribosomal 30S subunits but not for 70S ribosomes. Overexpression suppresses a cold-sensitive C23U 16S rRNA mutation and rimM deletion mutants. Its function probably overlaps Era.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cellular response to DNA damage stimulus
cytoplasm
maturation of SSU-rRNA
response to cold
ribosomal small subunit binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>402
atggcgaaagaatttggtcgcccgcagcgcgtagcgcaggaaatgcaaaaagagatcgct
ctcatcctgcagcgtgaaattaaagatcctcgcctgggcatgatgaccaccgtttccggt
gtcgaaatgtctcgcgacctggcgtatgccaaagtatatgtgacgttcctcaacgacaaa
gatgaagacgcggttaaagcgggcatcaaagcgttgcaagaagcttctggtttcatccgc
agcctgctggggaaagcgatgcgcctgcgtatcgtgccggaactgaccttcttctacgac
aactctctggttgaagggatgcgcatgtcaaacctggtgaccagcgtggtcaaacatgac
gaagaacgtcgtgttaacccggacgacagcaaggaggactaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:133
Protein Molecular Weight:15154
Protein Theoretical pI:Not Available
PDB File:1KKG
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Ribosome-binding factor A
MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDK
DEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHD
EERRVNPDDSKED
References
External Links:
ResourceLink
Uniprot ID:P0A7G2
Uniprot Name:RBFA_ECOLI
PDB ID:1KKG
CCDB:RBFA_ECOLI
General Reference:Not Available