Identification
Name:Protein RecA
Synonyms:Not Available
Gene Name:recA
Enzyme Class:Not Available
Biological Properties
General Function:SOS response
Specific Function:Required for homologous recombination and the bypass of mutagenic DNA lesions by the SOS response. Catalyzes ATP-driven homologous pairing and strand exchange of DNA molecules necessary for DNA recombinational repair. Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. The SOS response controls an apoptotic-like death (ALD) induced (in the absence of the mazE-mazF toxin-antitoxin module) in response to DNA damaging agents that is mediated by RecA and LexA (PubMed:22412352).
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
ATP binding
cell motility
cellular response to DNA damage stimulus
cytoplasm
damaged DNA binding
DNA recombination
DNA repair
DNA-dependent ATPase activity
response to ionizing radiation
single-stranded DNA binding
SOS response
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1062
atggctatcgacgaaaacaaacagaaagcgttggcggcagcactgggccagattgagaaa
caatttggtaaaggctccatcatgcgcctgggtgaagaccgttccatggatgtggaaacc
atctctaccggttcgctttcactggatatcgcgcttggggcaggtggtctgccgatgggc
cgtatcgtcgaaatctacggaccggaatcttccggtaaaaccacgctgacgctgcaggtg
atcgccgcagcgcagcgtgaaggtaaaacctgtgcgtttatcgatgctgaacacgcgctg
gacccaatctacgcacgtaaactgggcgtcgatatcgacaacctgctgtgctcccagccg
gacaccggcgagcaggcactggaaatctgtgacgccctggcgcgttctggcgcagtagac
gttatcgtcgttgactccgtggcggcactgacgccgaaagcggaaatcgaaggcgaaatc
ggcgactctcacatgggccttgcggcacgtatgatgagccaggcgatgcgtaagctggcg
ggtaacctgaagcagtccaacacgctgctgatcttcatcaaccagatccgtatgaaaatt
ggtgtgatgttcggtaacccggaaaccactaccggtggtaacgcgctgaaattctacgcc
tctgttcgtctcgacatccgtcgtatcggcgcggtgaaagagggcgaaaacgtggtgggt
agcgaaacccgcgtgaaagtggtgaagaacaaaatcgctgcgccgtttaaacaggctgaa
ttccagatcctctacggcgaaggtatcaacttctacggcgaactggttgacctgggcgta
aaagagaagctgatcgagaaagcaggcgcgtggtacagctacaaaggtgagaagatcggt
cagggtaaagcgaatgcgactgcctggctgaaagataacccggaaaccgcgaaagagatc
gagaagaaagtacgtgagttgctgctgagcaacccgaactcaacgccggatttctctgta
gatgatagcgaaggcgtagcagaaactaacgaagatttttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:353
Protein Molecular Weight:37973
Protein Theoretical pI:Not Available
PDB File:1AA3
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Protein RecA
MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMG
RIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQP
DTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLA
GNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVG
SETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIG
QGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
References
External Links:
ResourceLink
Uniprot ID:P0A7G6
Uniprot Name:RECA_ECOLI
PDB ID:1AA3
CCDB:RECA_ECOLI
General Reference:Not Available