| Identification |
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| Name: | RNase adapter protein RapZ |
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| Synonyms: | Not Available |
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| Gene Name: | rapZ |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | RNA processing |
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| Specific Function: | Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS (PubMed:17824929, PubMed:23475961). Displays ATPase and GTPase activities in vitro. Can also hydrolyze pNPP (PubMed:19074378). |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| ATP binding | | GTP binding | | identical protein binding | | positive regulation of biological process | | RNA binding | | RNA processing |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >855
atggtactgatgatcgtcagcggacgttcaggttcaggtaaatctgtcgccctgcgtgcg
ctggaagatatgggtttttactgcgtggataaccttcccgtagtgttgttacccgatctg
gctcgaaccctggccgatcgcgagatttctgccgccgtcagcattgatgttcgtaatatg
ccggagtcaccagaaatattcgaacaggcgatgagtaacctgcctgacgctttctcaccg
caactcctgttcctggatgccgaccgtaataccttaattcgtcgttacagtgacacgcgc
cgactgcatccgctttccagcaaaaacctgtcgctggaaagtgctatcgacaaagaaagc
gatttgctggagcctctgcgttcgcgagcggatctgattgtcgatacctcagaaatgtcc
gttcacgagctggctgaaatgctgcgtacccgtctgctgggtaaacgtgaacgcgaactg
accatggtctttgagtctttcggcttcaaacacggtatccctatcgatgcagattacgtc
tttgacgtgcgcttcttgccgaacccgcactgggatccgaaactgcgtccaatgacaggt
cttgataaacctgtcgccgcgttcctcgaccgccacacagaagtacacaattttatctac
cagacgcgaagctatcttgagctatggttacctatgctggaaaccaacaaccgtagctac
ttgacggtcgccattggttgtaccggcgggaagcaccgttcggtgtatattgcagagcaa
ctggcagactacttccgctcgcgcggtaaaaacgtccagtcacgccatcgtacgctggaa
aaacgtaaaccatga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 284 |
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| Protein Molecular Weight: | 32491 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >RNase adapter protein RapZ
MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNM
PESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKES
DLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYV
FDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSY
LTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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