Identification
Name:Endoribonuclease YbeY
Synonyms:Not Available
Gene Name:ybeY
Enzyme Class:Not Available
Biological Properties
General Function:translation
Specific Function:Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. Acts together with the RNase R to eliminate defective 70S ribosomes, but not properly matured 70S ribosomes or individual subunits, by a process mediated specifically by the 30S ribosomal subunit. Involved in the processing of 16S, 23S and 5S rRNAs, with a particularly strong effect on maturation at both the 5'-and 3'-ends of 16S rRNA as well as maturation of the 5'-end of 23S and 5S rRNAs.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
endonucleolytic cleavage involved in rRNA processing
endoribonuclease activity, producing 3'-phosphomonoesters
maturation of SSU-rRNA
metalloendopeptidase activity
nickel cation binding
response to heat
ribosomal small subunit biogenesis
ribosome biogenesis
rRNA processing
transcription antitermination
translation
zinc ion binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>468
atgagtcaggtgatcctcgatttacaactggcatgtgaagataattccgggttaccggaa
gagagccagtttcagacatggctgaatgcggtgatcccgcagtttcaggaagaatcggaa
gtgacgattcgcgtggtcgataccgccgaaagccacagtctgaatctgacctatcgcggt
aaggataagccgaccaacgtgctctccttcccgtttgaagtgccgcctggcatggaaatg
tcgctactgggcgatctggttatctgccgtcaggtggttgagaaggaagctcaggagcaa
ggcaaaccactggaggcgcactgggcgcatatggtggtgcacggcagtctgcatttgtta
ggttacgatcacatcgaagatgacgaagcagaagaaatggaagccctcgaaacagagatt
atgcttgctctgggctatgaggatccgtacattgccgagaaagaataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:155
Protein Molecular Weight:17525
Protein Theoretical pI:Not Available
PDB File:1XM5
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Endoribonuclease YbeY
MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRG
KDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGKPLEAHWAHMVVHGSLHLL
GYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
References
External Links:
ResourceLink
Uniprot ID:P0A898
Uniprot Name:YBEY_ECOLI
PDB ID:1XM5
CCDB:YBEY_ECOLI
General Reference:Not Available