| Identification |
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| Name: | Tyrosine recombinase XerC |
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| Synonyms: | Not Available |
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| Gene Name: | xerC |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | transposition, DNA-mediated |
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| Specific Function: | Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids at ColE1 xer (or cer) and pSC101 (or psi) sites. In the complex XerC specifically exchanges the top DNA strands (By similarity). |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| cell cycle | | cell division | | chromosome segregation | | cytoplasm | | DNA binding | | Holliday junction resolvase complex | | plasmid maintenance | | plasmid recombination | | resolution of recombination intermediates | | site-specific recombinase activity | | transposition, DNA-mediated | | tyrosine-based site-specific recombinase activity |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >897
atgaccgatttacacaccgatgtagaacgctacctacgttatctgagcgtggagcgccag
cttagcccgataaccctgcttaactaccagcgtcagcttgaggcgatcatcaattttgcc
agcgaaaacggcctgcaaagctggcagcaatgtgatgtgacgatggtgcgcaattttgct
gtacgcagtcgccgtaaagggctgggagcagcaagtctggcgttacggctttctgcgcta
cgtagcttttttgactggctggtcagccagaacgaactcaaagctaacccggcgaaaggt
gtttcggcaccgaaagcgccgcgtcatctgccgaaaaacatcgacgtcgacgatatgaat
cggctgctggatattgatatcaatgatcccctcgctgtacgcgaccgtgcaatgctggaa
gtgatgtacggcgcgggtctgcgtctttctgagctggtggggctggatattaaacacctc
gacctggagtctggtgaagtgtgggttatggggaaaggcagcaaagagcgccgcctgccg
attggtcgcaacgctgtggcgtggattgagcactggcttgatttgcgcgacctgtttggt
agcgaagacgacgcgctttttctgtcgaaactgggcaagcgtatctccgcgcgtaatgtg
cagaaacgctttgccgaatggggcataaaacaagggctgaataatcacgttcatccgcat
aaattacgtcactcgttcgccacgcatatgctggagtcgagcggcgatcttcgtggtgtg
caggagctgctgggtcatgccaacctctccaccacgcaaatctatactcatcttgatttt
caacaccttgcctcggtgtacgatgcggcgcatccacgcgccaaacgggggaaataa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 298 |
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| Protein Molecular Weight: | 33867 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Tyrosine recombinase XerC
MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDVTMVRNFA
VRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMN
RLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLP
IGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPH
KLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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