Proofreading thioesterase EntH (P0A8Y8)

Identification
Name:Proofreading thioesterase EntH
Synonyms:Not Available
Gene Name:entH
Enzyme Class:Not Available
Biological Properties
General Function:enterobactin biosynthetic process
Specific Function:Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Displays esterase activity toward a wide range of substrates, including acyl-CoAs and aryl-CoAs.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
enterobactin biosynthetic process
hydrolase activity, acting on ester bonds
identical protein binding
thiolester hydrolase activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>414
atgatctggaaacgccatttaacgctcgacgaactgaacgccaccagcgataacacaatg
gtggcgcatctgggaattgtgtatacccgtctgggcgatgatgtgctggaagccgaaatg
ccggttgatacccgtactcatcagccgttcggtttactacatggcggcgcgtcggcggcg
ctggcggaaacgctgggatcgatggccggatttatgatgacccgcgacggacagtgtgtg
gtaggcacagaacttaatgcaacacaccatcgcccggtgtctgagggaaaggtacgcggc
gtctgccagccgctgcatcttggtcggcaaaatcagagctgggaaatcgtcgttttcgat
gaacaggggcggcgttgctgcacttgtcggctgggtacggcagttttgggatga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:137
Protein Molecular Weight:14970
Protein Theoretical pI:Not Available
PDB File:1VH9
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Proofreading thioesterase EntH
MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDTRTHQPFGLLHGGASAA
LAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVCQPLHLGRQNQSWEIVVFD
EQGRRCCTCRLGTAVLG
References
External Links:
ResourceLink
Uniprot ID:P0A8Y8
Uniprot Name:ENTH_ECOLI
PDB ID:1VH9
CCDB:ENTH_ECOLI
General Reference:Not Available