| Identification |
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| Name: | Fumarate and nitrate reduction regulatory protein |
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| Synonyms: | Not Available |
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| Gene Name: | fnr |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | transcription, DNA-templated |
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| Specific Function: | Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism. When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| 4 iron, 4 sulfur cluster binding | | anaerobic respiration | | cytoplasm | | DNA binding | | iron-sulfur cluster binding | | metal ion binding | | regulation of transcription, DNA-templated | | response to nitric oxide | | sequence-specific DNA binding transcription factor activity | | transcription, DNA-templated |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >753
atgatcccggaaaagcgaattatacggcgcattcagtctggcggttgtgctatccattgc
caggattgcagcatcagccagctttgcatcccgttcacactcaacgaacatgagcttgat
cagcttgataatatcattgagcggaagaagcctattcagaaaggccagacgctgtttaag
gctggtgatgaacttaaatcgctttatgccatccgctccggtacgattaaaagttatacc
atcactgagcaaggcgacgagcaaatcactggtttccatttagcaggcgacctggtggga
tttgacgccatcggcagcggccatcacccgagcttcgcgcaggcgctggaaacctcgatg
gtatgtgaaatcccgttcgaaacgctggacgatttgtccggtaaaatgccgaatctgcgt
cagcagatgatgcgtctgatgagcggtgaaatcaaaggcgatcaggacatgatcctgctg
ttgtcgaagaaaaatgccgaggaacgtctggctgcattcatctacaacctgtcccgtcgt
tttgcccaacgcggcttctcccctcgtgaattccgcctgacgatgactcgtggcgatatc
ggtaactatctgggcctgacggtagaaaccatcagccgtctgctgggtcgcttccagaaa
agcggcatgctggcagtcaaaggtaaatacatcaccatcgaaaataacgatgcgctggcc
cagcttgctggtcatacgcgtaacgttgcctga |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 250 |
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| Protein Molecular Weight: | 27966 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Fumarate and nitrate reduction regulatory protein
MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFK
AGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSM
VCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILLLSKKNAEERLAAFIYNLSRR
FAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSGMLAVKGKYITIENNDALA
QLAGHTRNVA |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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