ECMDB: Anti-adapter protein IraP (P0AAN9)

Identification

Name:

Anti-adapter protein IraP

Synonyms:

Not Available

Gene Name:

iraP

Enzyme Class:

Not Available

Biological Properties

General Function:

positive regulation of transcription, DNA-templated

Specific Function:

Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
anti-sigma factor antagonist activity
cellular response to phosphate starvation
cytoplasm
negative regulation of protein catabolic process
positive regulation of transcription, DNA-templated

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>261
atgaaaaatctcattgctgagttgttatttaagcttgcccaaaaagaagaagagtcgaaa
gaactgtgtgcgcaggtagaagctttggagattatcgtcactgcaatgcttcgcaatatg
gcgcaaaatgaccaacagcggttgattgatcaggtagagggggcgctgtacgaggtaaag
cccgatgccagcattcctgacgacgatacggagctgctgcgcgattacgtaaagaagtta
ttgaagcatcctcgtcagtaa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

Protein Molecular Weight:

9937

Protein Theoretical pI:

Not Available

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Anti-adapter protein IraP
MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVK
PDASIPDDDTELLRDYVKKLLKHPRQ

References

External Links:

Resource	Link
Uniprot ID:	P0AAN9
Uniprot Name:	IRAP_ECOLI
CCDB:	IRAP_ECOLI

General Reference:

Not Available