| Identification |
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| Name: | Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK |
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| Synonyms: | Not Available |
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| Gene Name: | ybaK |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | translation |
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| Specific Function: | Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity. May compensate for the lack of Cys-tRNA(Pro) editing by ProRS. Is also able to deacylate Cys-tRNA(Cys), and displays weak deacylase activity in vitro against Gly-tRNA(Gly), as well as, at higher concentrations, some other correctly charged tRNAs. Unlike some of its orthologs it is not able to remove the amino acid moiety from incorrectly charged Ala-tRNA(Pro). |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| aminoacyl-tRNA editing activity | | Cys-tRNA(Pro) hydrolase activity | | cytoplasm | | lyase activity | | regulation of translational fidelity | | translation |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >480
atgacacccgcagttaaattactcgaaaaaaacaagatttcgtttcaaatccatacctac
gagcacgatccggctgaaaccaattttggcgatgaagtcgtcaaaaaattaggtttgaat
ccggatcaggtctacaaaacgctgctggtggcagtgaacggtgatatgaaacaccttgcc
gtggccgttacgccggtcgcaggtcaactggatcttaaaaaagtagcaaaagcgctgggt
gccaagaaagttgagatggccgatccgatggtcgcgcagcgttcgacgggatacctggtt
ggggggattagcccactggggcagaaaaaacgtctgccaacgattatcgacgcccccgca
caagaatttgccactatttatgtttccggcggcaagcgcggactggatatcgaactggcg
gcaggcgatctggcaaagatcctcgatgccaaatttgctgatatcgcccgccgcgattaa
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 159 |
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| Protein Molecular Weight: | 17092 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 2DXA |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK
MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQVYKTLLVAVNGDMKHLA
VAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGGISPLGQKKRLPTIIDAPA
QEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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