Identification
Name:Ribosomal silencing factor RsfS
Synonyms:Not Available
Gene Name:rsfS
Enzyme Class:Not Available
Biological Properties
General Function:negative regulation of translation
Specific Function:Functions as a ribosomal silencing factor. Addition to isolated ribosomal subunits partially inhibits their association, preventing translation. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8, preventing association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
mature ribosome assembly
negative regulation of ribosome biogenesis
negative regulation of translation
ribosomal large subunit binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>318
ttgcagggtaaagcactccaggattttgttatcgacaaaattgatgacctcaaaggtcag
gacatcatcgccttagacgttcagggcaaatccagcatcaccgactgcatgatcatctgt
acgggtacgtccagccgtcatgttatgtccattgctgaccacgttgtgcaggagtctcgc
gcagcgggcctgttaccgctcggcgtagaaggtgaaaacagcgccgactggattgtcgtg
gatttgggcgatgtgattgtccatgtcatgcaggaagagagccgtcgcctgtatgaactg
gaaaaactctggagttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:105
Protein Molecular Weight:11582
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Ribosomal silencing factor RsfS
MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTSSRHVMSIADHVVQESR
AAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEKLWS
References
External Links:
ResourceLink
Uniprot ID:P0AAT6
Uniprot Name:IOJAP_ECOLI
CCDB:IOJAP_ECOLI
General Reference:Not Available