Identification
Name:Penicillin-binding protein activator LpoB
Synonyms:Not Available
Gene Name:lpoB
Enzyme Class:Not Available
Biological Properties
General Function:regulation of cell shape
Specific Function:Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Stimulates transpeptidase and transglycosylase activities of PBP1b in vitro. May also contribute to outer membrane constriction during cell division, in complex with PBP1b.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell outer membrane
enzyme binding
enzyme regulator activity
peptidoglycan biosynthetic process
periplasmic side of cell outer membrane
regulation of catalytic activity
regulation of cell shape
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>642
atgacaaaaatgagtcgctacgccttgattaccgcgctggcgatgtttctcgccgggtgt
gtggggcaacgtgaacctgcaccggtagaagaagtgaaaccagcgccggaacaaccagcc
gagccacaacagcctgtccccacagtgccctcggtgccgacgatcccgcagcagccaggc
ccaattgagcacgaagatcaaactgcaccgcctgcgccgcatattcgccattatgactgg
aatggcgcaatgcagccgatggtcagtaagatgcttggggctgacggggtgactgcgggt
agcgtcctgctggttgatagcgttaacaaccgtactaacggttcgctgaatgccgcagaa
gcgaccgaaacgctgcgaaatgcgctggctaataacgggaaatttaccctggtttccgcc
cagcaactgtcgatggcgaagcaacagttaggtttgtcgccgcaggacagtttaggcacc
cgtagtaaagccataggcattgcccgcaatgtcggcgctcattacgtgctgtactccagc
gcctctggcaacgttaacgctccgaccctacaaatgcagctgatgctggtgcagacgggc
gaaattatctggtcaggtaaaggtgccgtttcgcagcaataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:213
Protein Molecular Weight:22515
Protein Theoretical pI:Not Available
Signaling Regions:
  • 1-19
Transmembrane Regions:Not Available
Protein Sequence:
>Penicillin-binding protein activator LpoB
MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQPVPTVPSVPTIPQQPG
PIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSVLLVDSVNNRTNGSLNAAE
ATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGTRSKAIGIARNVGAHYVLYSS
ASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ
References
External Links:
ResourceLink
Uniprot ID:P0AB38
Uniprot Name:LPOB_ECOLI
CCDB:LPOB_ECOLI
General Reference:Not Available