Identification
Name:Lipid II flippase FtsW
Synonyms:Not Available
Gene Name:ftsW
Enzyme Class:Not Available
Biological Properties
General Function:regulation of cell shape
Specific Function:Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. Required for localization of FtsI. May play a role in the stabilization of the FtsZ ring during cell division.
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:Not Available
Transports:
Transport References:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell division
cell division site
cell wall organization
FtsZ-dependent cytokinesis
integral component of plasma membrane
lipid-linked peptidoglycan transport
lipid-linked peptidoglycan transporter activity
peptidoglycan biosynthetic process
regulation of cell shape
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1245
atgcgtttatctctccctcgcctgaaaatgccgcgcctgccaggattcagtatcctggtc
tggatctccacggcgctaaagggctgggtgatgggctcgcgggaaaaagataccgacagc
ctgatcatgtacgatcgcaccttactgtggctgaccttcggcctcgcggcgattggcttt
atcatggtgacctcggcgtcaatgcccatagggcaacgcttaaccaacgatccgttcttc
ttcgcgaagcgtgatggtgtctatctgattttggcgtttattctggcgatcattacgctg
cgtctgccgatggagttctggcaacgctacagtgccacgatgctgctcggatctatcatc
ctgctgatgatcgtcctggtagtgggtagctcggttaaaggggcatcgcgttggatcgat
ctcggtttgctgcgtatccagcctgcggagctgacaaaactgtcgctgttttgctatatc
gccaactatctggtgcgtaaaggcgacgaagtacgtaataacctgcgcggcttcctgaaa
ccgatgggcgtgattctggtgttggcagtgttactgctggcacagccagaccttggtacg
gtggtggtgttgtttgtgactacgctggcgatgttgttcctggcgggagcgaaattgtgg
cagttcattgccattatcggtatgggcatttcagcggttgtgttgctgatactcgccgaa
ccgtaccgtatccgccgtgttaccgcattctggaacccgtgggaagatccctttggcagc
ggctatcagttaacgcaatcgctgatggcgtttggtcgcggcgaactttgggggcaaggt
ttaggtaactcggtacaaaaactggagtatctgccggaagcgcacactgactttattttc
gccattatcggcgaagaactggggtatgtcggtgtggtgctggcacttttaatggtattc
ttcgtcgcttttcgcgcgatgtcgattggccgtaaagcattagaaattgaccaccgtttt
tccggttttctcgcctgttctattggcatctggtttagcttccaggcgctggttaacgta
ggcgcggcggcggggatgttaccgaccaaaggtctgacattgccgctgatcagttacggt
ggttcgagcttactgattatgtcgacagccatcatgatgctgttgcgtattgattatgaa
acgcgtctggagaaagcgcaggcgtttgtacgaggttcacgatga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:414
Protein Molecular Weight:45986
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 13-33
  • 48-68
  • 87-107
  • 112-132
  • 175-194
  • 198-217
  • 222-244
  • 302-322
  • 343-363
  • 374-394
Protein Sequence:
>Lipid II flippase FtsW
MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMYDRTLLWLTFGLAAIGF
IMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRLPMEFWQRYSATMLLGSII
LLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYIANYLVRKGDEVRNNLRGFLK
PMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVVLLILAE
PYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQKLEYLPEAHTDFIF
AIIGEELGYVGVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNV
GAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMMLLRIDYETRLEKAQAFVRGSR
References
External Links:
ResourceLink
Uniprot ID:P0ABG4
Uniprot Name:FTSW_ECOLI
CCDB:FTSW_ECOLI
General Reference:Not Available