Identification
Name:HTH-type transcriptional repressor CytR
Synonyms:Not Available
Gene Name:cytR
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
negative regulation of transcription, DNA-templated
sequence-specific DNA binding transcription factor activity
transcription regulatory region sequence-specific DNA binding
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1026
gtgaaagcgaagaagcaggaaactgccgcgaccatgaaagacgttgccctcaaggcaaaa
gtctctacagcgaccgtctcccgagcattaatgaatcccgataaagtctcccaggccacc
cgtaatcgggttgaaaaagcggcccgggaagtgggttatttaccgcagcctatggggcgc
aacgtcaagcgtaatgaatcccgcaccattctggtgattgtcccggatatctgcgatccc
ttctttagcgaaattattcgcggtatcgaagttacggcggcaaatcacggatatctggtg
ctgattggcgactgtgcgcatcaaaatcagcaggaaaaaacctttatcgatttgatcatc
accaagcaaattgatggcatgttgttgctgggttcaaggctgccgtttgatgccagcatt
gaggaacagcgtaatctgccgccgatggtgatggcgaacgaatttgcaccggagctggag
ctgcctacagttcatatcgacaatctgaccgccgcatttgatgcagtaaattatttatat
gagcaagggcataaacggattggctgtatagccggtcccgaagagatgccgctgtgtcac
taccgcctgcaaggctatgttcaggcgctgcgtcgctgcggcattatggttgatccgcaa
tacatcgcccgtggcgacttcaccttcgaagccggaagcaaagcgatgcagcagctgctt
gatcttccacaaccgcctactgctgtcttctgccatagcgatgtgatggcgctcggcgca
ctttctcaggcaaaacgccaggggctgaaagtcccggaagacctttccataatcggtttt
gataacatcgacctgacgcaattttgtgatccgccgctgacaaccatcgcgcagccgcgt
tacgaaatcggtcgggaagctatgctgttattgcttgatcaaatgcaggggcaacacgtt
ggcagtggctctcgtttaatggactgcgaacttatcatccggggatcaacacgcgcgtta
ccttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:341
Protein Molecular Weight:37819
Protein Theoretical pI:Not Available
PDB File:2LCV
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>HTH-type transcriptional repressor CytR
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGR
NVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLII
TKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELELPTVHIDNLTAAFDAVNYLY
EQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPR
YEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIRGSTRALP
References
External Links:
ResourceLink
Uniprot ID:P0ACN7
Uniprot Name:CYTR_ECOLI
PDB ID:2LCV
CCDB:CYTR_ECOLI
General Reference:Not Available