| Identification |
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| Name: | 50S ribosomal protein L14 |
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| Synonyms: | Not Available |
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| Gene Name: | rplN |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | translation |
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| Specific Function: | This protein binds directly to 23S ribosomal RNA. In the E.coli 70S ribosome it has been modeled to make two contacts with the 16S rRNA of the 30S subunit, forming part of bridges B5 and B8, connecting the 2 subunits (PubMed:12809609). Although the protein undergoes significant rotation during the transition from an initiation to and EF-G bound state, the bridges remain stable. In the 3.5 A resolved structures L14 and L19 interact and together make contact with the 16S rRNA in bridges B5 and B8 (PubMed:16272117).Can also interact with RsfS, in this case bridge B8 probably cannot form, and the 30S and 50S ribosomal subunits do not associate, which represses translation. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | |
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| Metabolites: | |
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| GO Classification: | | Function |
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| cytosolic large ribosomal subunit | | large ribosomal subunit rRNA binding | | structural constituent of ribosome | | translation |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >372
atgatccaagaacagactatgctgaacgtcgccgacaactccggtgcacgtcgcgtaatg
tgtatcaaggttctgggtggctcgcaccgtcgctacgcaggcgtaggcgacatcatcaag
atcaccatcaaagaagcaattccgcgtggtaaggtcaaaaaaggtgatgtgctgaaggcg
gtagtggtgcgcaccaagaagggtgttcgtcgcccggacggttctgtcattcgcttcgat
ggtaatgcttgtgttcttctgaacaacaacagcgagcagcctatcggtacgcgtattttt
gggccggtaactcgtgagcttcgtagtgagaagttcatgaaaattatctctctggcacca
gaagtactctaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 123 |
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| Protein Molecular Weight: | 13540 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1ML5 |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >50S ribosomal protein L14
MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKA
VVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAP
EVL |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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