Identification
Name:Multidrug export protein EmrB
Synonyms:Not Available
Gene Name:emrB
Enzyme Class:Not Available
Biological Properties
General Function:transmembrane transport
Specific Function:Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
integral component of membrane
plasma membrane
response to antibiotic
response to toxic substance
transmembrane transport
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1539
atgcaacagcaaaaaccgctggaaggcgcgcaactggtcattatgacgattgcgctgtca
ctggcgacattcatgcaggtgctggactccaccattgctaacgtggcgatccccactatc
gccgggaatctgggctcatcgctcagccagggaacgtgggtaatcacttctttcggggtg
gcgaatgccatctcgatcccgcttaccggctggctggcaaagcgcgtcggggaagtgaaa
ctgttcctttggtccaccatcgcctttgctattgcgtcgtgggcgtgtggtgtctccagc
agcctgaatatgctgatcttcttccgcgtgattcaggggattgtcgccgggccgttgatc
ccgctttcgcaaagtctattgctgaataactacccgccagccaaacgctcgatcgcgctg
gcgttgtggtcgatgacggtgattgtcgcgccaatttgcggcccgatcctcggcggttat
atcagcgataattaccactggggctggatattcttcatcaacgtgccgattggcgtggcg
gtggtgttgatgacactgcaaactctgcgcggacgtgaaacccgcaccgaacggcggcgg
attgatgccgtggggctggcactgctggttattggtatcggcagcctgcagattatgctc
gaccgcggtaaagagctggactggttttcatcacaggaaattatcatccttaccgtggtg
gcggtggtggctatctgcttcctgattgtctgggagctgaccgacgataacccgatagtc
gatctgtcgttgtttaagtcgcgcaacttcaccatcggctgcttgtgtatcagcctcgcg
tatatgctctacttcggcgctattgttctgctgccgcagttgttgcaggaggtctacggt
tacacggcgacctgggcaggtttggcctctgcgccggtagggattattccggtgatcctg
tcgccgattatcggccgcttcgcgcataaactggatatgcggcggctggtaaccttcagc
tttattatgtatgccgtctgcttctactggcgtgcctatacctttgaaccaggtatggat
tttggcgcgtcggcctggccgcagtttatccaggggtttgcggtggcctgcttctttatg
ccgctgaccaccattacgctgtctggtttgccaccggaacgactggcggcggcatcgagc
ctctctaactttacgcgaacgctggcggggtctatcggcacgtcgataaccacgaccatg
tggaccaaccgcgagtcgatgcaccatgcgcagttgactgagtcggtaaacccgttcaac
ccgaatgcccaggcgatgtacagtcaactggaagggcttgggatgacgcaacagcaggca
tcaggctggattgcccagcagatcaccaatcaggggctgattatttccgccaatgagatc
ttctggatgtcagccgggatattcctcgtcctgctggggctggtgtggtttgctaaaccg
ccatttggcgcaggtggcggcggaggcggtgcgcactaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:512
Protein Molecular Weight:55623
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 13-38
  • 52-72
  • 82-100
  • 110-128
  • 137-159
  • 165-189
  • 203-223
  • 234-249
  • 272-295
  • 306-329
  • 336-355
  • 364-387
  • 408-428
  • 482-504
Protein Sequence:
>Multidrug export protein EmrB
MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGV
ANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLI
PLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVA
VVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVV
AVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYG
YTATWAGLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMD
FGASAWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTM
WTNRESMHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEI
FWMSAGIFLVLLGLVWFAKPPFGAGGGGGGAH
References
External Links:
ResourceLink
Uniprot ID:P0AEJ0
Uniprot Name:EMRB_ECOLI
CCDB:EMRB_ECOLI
General Reference:Not Available