Identification
Name:Acid stress chaperone HdeB
Synonyms:Not Available
Gene Name:hdeB
Enzyme Class:Not Available
Biological Properties
General Function:response to pH
Specific Function:Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cellular response to stress
periplasmic space
response to pH
unfolded protein binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>327
atgaatatttcatctctccgtaaagcgtttatttttatgggcgctgtagcggctttgtca
ctggtgaacgcacaatctgcgttggcagccaatgaatccgctaaagatatgacctgccag
gaatttattgatctgaatccaaaagcaatgaccccggttgcatggtggatgctgcatgaa
gaaacagtatataaaggtggcgataccgttactttaaatgaaaccgatctcactcaaatt
cctaaagtgatcgaatactgtaagaaaaacccgcagaaaaatttgtataccttcaaaaat
caagcatctaatgacttgccgaattaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:108
Protein Molecular Weight:12042
Protein Theoretical pI:Not Available
PDB File:2XUV
Signaling Regions:
  • 1-29
Transmembrane Regions:Not Available
Protein Sequence:
>Acid stress chaperone HdeB
MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFIDLNPKAMTPVAWWMLHE
ETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQASNDLPN
References
External Links:
ResourceLink
Uniprot ID:P0AET2
Uniprot Name:HDEB_ECOLI
PDB ID:2XUV
CCDB:HDEB_ECOLI
General Reference:Not Available