Identification |
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Name: | Chaperone protein Skp |
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Synonyms: | Not Available |
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Gene Name: | skp |
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Enzyme Class: | Not Available |
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Biological Properties |
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General Function: | protein stabilization |
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Specific Function: | Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. Required for the efficient release of OmpA from the inner membrane, the maintenance of its solubility in the periplasm, and, in association with lipopolysaccharide (LPS), for the efficient folding and insertion of OmpA into the outer membrane. |
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Cellular Location: | Not Available |
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SMPDB Pathways: | Not Available |
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KEGG Pathways: | Not Available |
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Metabolites: | |
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GO Classification: | Function |
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chaperone mediated protein folding requiring cofactor | cytosol | Gram-negative-bacterium-type cell outer membrane assembly | intracellular protein transmembrane transport | lipopolysaccharide binding | outer membrane-bounded periplasmic space | protein folding | protein insertion into membrane from inner side | protein maturation by protein folding | protein stabilization | unfolded protein binding |
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Gene Properties |
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Blattner: | Not Available |
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Gene Orientation | Not Available |
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Centisome Percentage: | Not Available |
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Left Sequence End | Not Available |
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Right Sequence End | Not Available |
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Gene Sequence: | >486
gtgaaaaagtggttattagctgcaggtctcggtttagcactggcaacttctgctcaggcg
gctgacaaaattgcaatcgtcaacatgggcagcctgttccagcaggtagcgcagaaaacc
ggtgtttctaacacgctggaaaatgagttcaaaggccgtgccagcgaactgcagcgtatg
gaaaccgatctgcaggctaaaatgaaaaagctgcagtccatgaaagcgggcagcgatcgc
actaagctggaaaaagacgtgatggctcagcgccagacttttgctcagaaagcgcaggct
tttgagcaggatcgcgcacgtcgttccaacgaagaacgcggcaaactggttactcgtatc
cagactgctgtgaaatccgttgccaacagccaggatatcgatctggttgttgatgcaaac
gccgttgcttacaacagcagcgatgtaaaagacatcactgccgacgtactgaaacaggtt
aaataa |
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Protein Properties |
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Pfam Domain Function: | Not Available |
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Protein Residues: | 161 |
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Protein Molecular Weight: | 17688 |
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Protein Theoretical pI: | Not Available |
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PDB File: | 1SG2 |
Signaling Regions: | |
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Transmembrane Regions: | Not Available |
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Protein Sequence: | >Chaperone protein Skp
MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSNTLENEFKGRASELQRM
ETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFEQDRARRSNEERGKLVTRI
QTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQVK |
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References |
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External Links: | |
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General Reference: | Not Available |
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