Identification |
---|
Name: | Regulator of RpoS |
---|
Synonyms: | Not Available |
---|
Gene Name: | rssB |
---|
Enzyme Class: | Not Available |
---|
Biological Properties |
---|
General Function: | regulation of nucleic acid-templated transcription |
---|
Specific Function: | Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. In stationary phase, could also act as an anti-sigma factor and reduce the ability of RpoS to activate gene expression. Is also involved in the regulation of the mRNA polyadenylation pathway during stationary phase, probably by maintaining the association of PcnB with the degradosome. |
---|
Cellular Location: | Not Available |
---|
SMPDB Pathways: | Not Available |
---|
KEGG Pathways: | Not Available |
---|
Metabolites: | |
---|
GO Classification: | Function |
---|
intracellular | phosphorelay signal transduction system | positive regulation of proteolysis | protein destabilization | regulation of gene expression | regulation of nucleic acid-templated transcription | sigma factor antagonist activity |
|
---|
Gene Properties |
---|
Blattner: | Not Available |
---|
Gene Orientation | Not Available |
---|
Centisome Percentage: | Not Available |
---|
Left Sequence End | Not Available |
---|
Right Sequence End | Not Available |
---|
Gene Sequence: | >1014
atgacgcagccattggtcggaaaacagattctcattgttgaagatgagcaggtatttcgc
tcgcttctggattcatggttttcctcattgggagcgacaacggtactggcggctgatggg
gtggatgcccttgagttgctgggaggtttcactccagacctgatgatatgtgatatcgcg
atgccacgaatgaacgggcttaaactgctggagcatatacgtaacagaggcgaccagacc
ccagttctggtgatatctgccactgaaaatatggcagatattgccaaagcgttacgtctg
ggcgttgaagatgttttgctgaaaccagttaaagatctgaatcgcttgcgcgagatggtt
tttgcctgtctctatcccagcatgtttaattcgcgcgttgaggaagaggaaaggcttttt
cgcgactgggatgcaatggttgataaccctgccgcagcggcgaaattattacaggaacta
caaccgccggttcagcaggtgatttcccattgccgggttaattatcgtcaattggttgcc
gcggacaaacccggcctggtgcttgatattgccgcactttcggaaaacgatctggcattt
tattgccttgatgtcacccgagctggacataatggcgtacttgctgccttgttattacgc
gcattgtttaacggattattacaggaacagcttgcacaccaaaatcaacggttgccagag
ttgggcgcgttattgaagcaggtaaaccatttacttcgtcaggccaatctgccggggcag
tttccgctattagttggctattatcatcgcgaactgaaaaatctcattctggtttctgcg
ggtctgaatgcgacgttaaataccggcgaacaccaggtgcaaatcagtaatggtgttccg
ttaggcactttaggtaacgcttatttgaatcaattgagccagcgatgcgatgcctggcaa
tgccaaatatggggaaccggtggtcgactgcgcttgatgttgtctgcagaatga |
---|
Protein Properties |
---|
Pfam Domain Function: | Not Available |
---|
Protein Residues: | 337 |
---|
Protein Molecular Weight: | 37301 |
---|
Protein Theoretical pI: | Not Available |
---|
PDB File: | 3EOD |
Signaling Regions: | Not Available |
---|
Transmembrane Regions: | Not Available |
---|
Protein Sequence: | >Regulator of RpoS
MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIA
MPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMV
FACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQELQPPVQQVISHCRVNYRQLVA
ADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPE
LGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVP
LGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLMLSAE |
---|
References |
---|
External Links: | |
---|
General Reference: | Not Available |
---|