| Identification |
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| Name: | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE |
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| Synonyms: | Not Available |
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| Gene Name: | tsaE |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | threonylcarbamoyladenosine biosynthetic process |
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| Specific Function: | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| ATP binding | | cytoplasm | | metal ion binding | | threonylcarbamoyladenosine biosynthetic process |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >462
atgatgaatcgagtaattccgctccctgatgagcaggcaacattagacctgggcgagcgg
gtagcgaaagcctgcgatggcgcaaccgtaatctatctgtatggcgatttaggcgcaggt
aaaaccacctttagccggggctttttacaggctctgggtcatcagggtaatgtcaaaagc
cccacttatacgctggtcgaaccctatacgctcgacaacttaatggtctatcactttgat
ttgtaccgccttgccgatcccgaggagctggagtttatggggatccgcgattattttgcc
aacgatgccatctgcctggtggagtggccacaacaaggtacaggtgttcttcctgacccg
gatgtcgaaatacacattgattatcaggcacaaggccgtgaggcgcgcgtgagtgcggtt
tcctctgcgggtgaattgttgctggcgcgtttagccggttaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 153 |
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| Protein Molecular Weight: | 16852 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTFSRGFLQALGHQGNVKS
PTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFANDAICLVEWPQQGTGVLPDP
DVEIHIDYQAQGREARVSAVSSAGELLLARLAG |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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