Identification
Name:Regulator of ribonuclease activity B
Synonyms:Not Available
Gene Name:rraB
Enzyme Class:Not Available
Biological Properties
General Function:regulation of endoribonuclease activity
Specific Function:Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
endoribonuclease inhibitor activity
enzyme binding
mRNA catabolic process
negative regulation of catalytic activity
negative regulation of endoribonuclease activity
regulation of catalytic activity
regulation of endoribonuclease activity
ribonuclease inhibitor activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>417
atggcaaacccggaacaactggaagaacagcgtgaagaaacacgtttgattattgaagaa
ttactggaagatggcagcgatccggacgcgctgtacaccatcgaacaccatctttccgca
gacgatctggaaaccctggaaaaagcagcagttgaagcgtttaaactcggttacgaagtg
accgatccagaagagctggaagttgaagatggtgatatcgtgatttgctgcgacatcctc
agcgagtgcgcgttgaatgccgatctgatcgatgcccaggttgaacaactgatgacgctg
gcagagaaatttgacgttgagtacgacggatggggcacttactttgaagatcctaacggc
gaagatggcgacgatgaagattttgtcgatgaagacgatgacggagttcgccactaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:138
Protein Molecular Weight:15602
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Regulator of ribonuclease activity B
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEV
TDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNG
EDGDDEDFVDEDDDGVRH
References
External Links:
ResourceLink
Uniprot ID:P0AF90
Uniprot Name:RRAB_ECOLI
CCDB:RRAB_ECOLI
General Reference:Not Available