| Identification |
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| Name: | Stringent starvation protein B |
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| Synonyms: | Not Available |
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| Gene Name: | sspB |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | positive regulation of protein catabolic process |
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| Specific Function: | Enhances recognition of ssrA-tagged proteins by the ClpX-ClpP protease; the ssrA degradation tag (AANDENYALAA) is added trans-translationally to proteins that are stalled on the ribosome, freeing the ribosome and targeting stalled peptides for degradation. SspB activates the ATPase activity of ClpX. Seems to act in concert with SspA in the regulation of several proteins during exponential and stationary-phase growth.Also stimulates degradation of the N-terminus of RseA (residues 1-108, alone or in complex with sigma-E) by ClpX-ClpP in a non-ssrA-mediated fashion. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| positive regulation of protein catabolic process | | ribosome |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >498
atggatttgtcacagctaacaccacgtcgtccctatctgctgcgtgcattctatgagtgg
ttgctggataaccagctcacgccgcacctggtggtggatgtgacgctccctggcgtgcag
gttcctatggaatatgcgcgtgacgggcaaatcgtactcaacattgcgccgcgtgctgtc
ggcaatctggaactggcgaatgatgaggtgcgctttaacgcgcgctttggtggcattccg
cgtcaggtttctgtgccgctggctgccgtgctggctatctacgcccgtgaaaatggcgca
ggcacgatgtttgagcctgaagctgcctacgatgaagataccagcatcatgaatgatgaa
gaggcatcggcagacaacgaaaccgttatgtcggttattgatggcgacaagccagatcac
gatgatgacactcatcctgacgatgaacctccgcagccaccacgcggtggtcgaccggca
ttacgcgttgtgaagtaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 165 |
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| Protein Molecular Weight: | 18262 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1OX8 |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Stringent starvation protein B
MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPMEYARDGQIVLNIAPRAV
GNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGTMFEPEAAYDEDTSIMNDE
EASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPALRVVK |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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