Identification
Name:Protein translocase subunit SecE
Synonyms:Not Available
Gene Name:secE
Enzyme Class:Not Available
Biological Properties
General Function:protein transport by the Sec complex
Specific Function:Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell envelope Sec protein transport complex
integral component of membrane
integral component of plasma membrane
intracellular
intracellular protein transmembrane transport
intracellular protein transport
P-P-bond-hydrolysis-driven protein transmembrane transporter activity
plasma membrane
protein secretion
protein targeting
protein transport by the Sec complex
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>384
atgagtgcgaataccgaagctcaaggaagcgggcgcggcctggaagcgatgaagtgggtc
gttgtggtggcattgctcctggtggcgattgtcggcaactatctttatcgcgacattatg
ctgccgctgcgtgcgctggccgtagtaattctgattgctgcagcgggtggtgtcgcgctg
ttaacgacaaaaggtaaagctaccgttgcttttgcccgtgaagcgcgtaccgaagtccgt
aaggtcatttggccgactcgccaggaaacattgcacaccacgctgattgtggctgcggtt
accgcagtaatgtcactgatcctgtggggactggatggtattctggttcgcctggtatcc
tttatcactggcctgaggttctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:127
Protein Molecular Weight:13643
Protein Theoretical pI:Not Available
PDB File:2AKH
Signaling Regions:Not Available
Transmembrane Regions:
  • 20-32
  • 49-60
  • 98-115
Protein Sequence:
>Protein translocase subunit SecE
MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLRALAVVILIAAAGGVAL
LTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRLVS
FITGLRF
References
External Links:
ResourceLink
Uniprot ID:P0AG96
Uniprot Name:SECE_ECOLI
PDB ID:2AKH
CCDB:SECE_ECOLI
General Reference:Not Available