Peroxiredoxin osmC (P0C0L2)

Identification
Name:Peroxiredoxin osmC
Synonyms:
  • Osmotically-inducible protein C
Gene Name:osmC
Enzyme Class:
Biological Properties
General Function:Posttranslational modification, protein turnover, chaperones
Specific Function:Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide
Cellular Location:Cytoplasm
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
ECMDB00494WaterMetaboCard
GO Classification:
Process
response to stimulus
response to stress
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>432 bp
ATGACAATCCATAAGAAAGGTCAGGCACACTGGGAAGGCGATATCAAACGCGGGAAGGGA
ACAGTATCCACCGAGAGTGGCGTGCTGAACCAACAGCCGTATGGATTTAACACGCGTTTT
GAAGGCGAAAAAGGAACCAACCCTGAAGAACTGATTGGCGCAGCGCATGCCGCATGTTTC
TCAATGGCGCTTTCATTAATGCTGGGGGAAGCGGGATTCACGCCAACATCGATTGATACC
ACCGCCGATGTGTCGCTGGATAAAGTGGATGCCGGTTTTGCGATTACGAAAATCGCACTG
AAGAGTGAAGTTGCGGTGCCGGGTATTGATGCCTCTACCTTTGACGGCATAATCCAGAAA
GCAAAAGCAGGATGCCCGGTCTCTCAGGTACTGAAAGCGGAAATTACGCTGGATTACCAG
TTGAAATCGTAA
Protein Properties
Pfam Domain Function:
Protein Residues:143
Protein Molecular Weight:15088
Protein Theoretical pI:6
PDB File:1NYE
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Peroxiredoxin osmC
MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEKGTNPEELIGAAHAACF
SMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKSEVAVPGIDASTFDGIIQK
AKAGCPVSQVLKAEITLDYQLKS
References
External Links:
ResourceLink
Uniprot ID:P0C0L2
Uniprot Name:OSMC_ECOLI
GenBank Gene ID:U00096
Genebank Protein ID:1787757
PDB ID:1NYE
CCDB:OSMC_ECOLI
General Reference:
  • Aiba, H., Baba, T., Hayashi, K., Inada, T., Isono, K., Itoh, T., Kasai, H., Kashimoto, K., Kimura, S., Kitakawa, M., Kitagawa, M., Makino, K., Miki, T., Mizobuchi, K., Mori, H., Mori, T., Motomura, K., Nakade, S., Nakamura, Y., Nashimoto, H., Nishio, Y., Oshima, T., Saito, N., Sampei, G., Horiuchi, T., et, a. l. .. (1996). "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." DNA Res 3:363-377. Pubmed: 9097039
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Gutierrez, C., Devedjian, J. C. (1991). "Osmotic induction of gene osmC expression in Escherichia coli K12." J Mol Biol 220:959-973. Pubmed: 1715407
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Lesniak, J., Barton, W. A., Nikolov, D. B. (2003). "Structural and functional features of the Escherichia coli hydroperoxide resistance protein OsmC." Protein Sci 12:2838-2843. Pubmed: 14627744
  • Link, A. J., Robison, K., Church, G. M. (1997). "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12." Electrophoresis 18:1259-1313. Pubmed: 9298646
  • Shin, D. H., Choi, I. G., Busso, D., Jancarik, J., Yokota, H., Kim, R., Kim, S. H. (2004). "Structure of OsmC from Escherichia coli: a salt-shock-induced protein." Acta Crystallogr D Biol Crystallogr 60:903-911. Pubmed: 15103136
  • Zhang, J., Sprung, R., Pei, J., Tan, X., Kim, S., Zhu, H., Liu, C. F., Grishin, N. V., Zhao, Y. (2009). "Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli." Mol Cell Proteomics 8:215-225. Pubmed: 18723842