Identification
Name:Signal recognition particle receptor FtsY
Synonyms:Not Available
Gene Name:ftsY
Enzyme Class:Not Available
Biological Properties
General Function:SRP-dependent cotranslational protein targeting to membrane
Specific Function:Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytosol
GTP binding
GTPase activity
intrinsic component of plasma membrane
metabolic process
SRP-dependent cotranslational protein targeting to membrane
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1494
atggcgaaagaaaaaaaacgtggctttttttcctggctgggctttggtcaaaaagagcag
accccggaaaaagagacagaagttcagaatgaacaaccggttgtagaagaaatcgttcag
gcgcaagagcctgtgaaggcctctgaacaagccgttgaagagcagccgcaagcgcatact
gaagccgaggcggaaacttttgctgccgacgttgtggaagtcactgaacaggttgctgaa
agtgaaaaagcgcagcctgaagcggaagtcgttgcacagccggaaccggtcgtagaagaa
acgccggagccagtggctatcgaacgtgaagagctgccgttgccggaagacgtcaacgcc
gaagcggtttcgccagaagagtggcaggctgaagcggaaaccgtagagattgtcgaagcg
gcggaagaagaagcggctaaagaagaaattaccgacgaagagctggaaacggcgctggct
gccgaagcggcagaagaggcggtgatggtggttcctccggcagaagaagagcagccggtg
gaagaaatcgctcaggagcaggaaaaaccgaccaaagaaggttttttcgcgcgcctgaaa
cgcagcctgttaaaaaccaaagaaaatctcggttccggatttatcagcctgttccgcggt
aaaaaaatcgacgatgatctgtttgaggagctggaagagcagcttttgatcgccgatgtg
ggtgtggaaaccacacgtaaaattatcaccaatctgacggaaggcgcatcccgcaagcag
cttcgtgacgccgaggcgctctatggcctgctgaaagaagagatgggcgagattctggcg
aaagtcgatgagccgctgaatgttgaaggcaaagcgccgtttgtgatcctgatggtgggc
gtcaacggtgtgggtaaaaccacgacgattggtaagctggcgcgtcagtttgagcagcag
ggtaaatcggtgatgctggcggcgggtgatactttccgtgcagctgcggttgaacagctt
caggtctggggtcagcgcaacaatattccggtgattgcccagcataccggggcggattcc
gcctctgttatcttcgacgccattcaggcagctaaagcgcgtaatatcgacgtcctgatt
gccgatacagccggacgcctgcagaacaaatcgcacctgatggaagagttgaagaaaatc
gtccgcgtgatgaagaaactcgacgttgaagcgccgcatgaagttatgctgactattgat
gccagcaccgggcagaacgcggtaagccaggccaaactgttccatgaagccgttggctta
accggcatcacgctaacgaaactggacggcacggcgaaaggcggggtaattttctcggtg
gctgaccagtttggtatccctatccgctacattggtgtcggcgaacgtattgaggatttg
cgtccgtttaaggcggacgactttatagaggcactttttgcccgagaggattaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:497
Protein Molecular Weight:54512
Protein Theoretical pI:Not Available
PDB File:1FTS
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Signal recognition particle receptor FtsY
MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHT
EAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNA
EAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVMVVPPAEEEQPV
EEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIADV
GVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKAPFVILMVG
VNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADS
ASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKKIVRVMKKLDVEAPHEVMLTID
ASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIEDL
RPFKADDFIEALFARED
References
External Links:
ResourceLink
Uniprot ID:P10121
Uniprot Name:FTSY_ECOLI
PDB ID:1FTS
CCDB:FTSY_ECOLI
General Reference:Not Available