Identification
Name:Selenocysteine-specific elongation factor
Synonyms:Not Available
Gene Name:selB
Enzyme Class:Not Available
Biological Properties
General Function:selenocysteine metabolic process
Specific Function:Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cytoplasm
GDP binding
GTP binding
GTPase activity
selenocysteine incorporation
selenocysteine insertion sequence binding
selenocysteine metabolic process
translation elongation factor activity
tRNA binding
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1845
atgattattgcgactgccggacacgttgaccacggcaaaacaaccttattgcaggcgatt
actggcgtaaatgctgaccgtctgccggaagaaaaaaagcgcggcatgaccatcgatctc
ggctatgcctactggccgcagccggatggtcgcgtgcctggttttatcgacgttcccggt
catgaaaagtttctttccaacatgctggcgggcgttggtggtatcgatcacgcgctgttg
gtggtggcgtgcgatgacggcgtgatggcacagacccgtgagcatctggcgattttgcag
ctgaccggtaacccgatgctgacagtggcgctgaccaaagccgatcgcgtggacgaagcg
cgtgttgatgaggttgaacgccaggtaaaggaggttctgcgggaatacggttttgctgag
gcaaaactgtttatcaccgcagcaaccgaaggtcggggaatggatgccctgcgcgagcat
ctgcttcagttgccggaacgcgagcacgccagccaacatagtttccgcctcgcgattgac
cgcgcatttaccgtaaaaggtgccgggctggtcgtcaccggtacggcgttaagcggggaa
gtgaaggtaggcgattcactctggctgactggtgtaaataaaccgatgcgtgtacgtgcg
ctgcatgcgcaaaaccagccaacagaaaccgccaatgccgggcagcgtatcgcgcttaac
atcgcgggtgatgcggaaaaagagcagattaaccgtggcgactggctgcttgccgatgtg
ccgccagagccgttcacacgggtgattgtcgagcttcaaacccatacaccgctgacccag
tggcagccgctgcatattcaccacgccgccagccacgtcacgggacgcgtttcactgctg
gaagataaccttgctgaactggtcttcgacaccccgttatggctggcagataacgaccgc
ctggtattgcgcgatatctctgcccgcaacacgctggccggagcgcgcgtcgtgatgctt
aacccgccgcgtcgcggtaaacgtaagccggaatatctgcaatggctggcgtctcttgca
cgggcgcagagcgatgccgatgcgttatctgttcatctggaacgcggcgcggttaacctt
gcggatttcgcctgggcgcgccagctcaacggcgaagggatgcgcgaattgctgcaacag
cctggttatattcaggctggttatagcttgttgaatgcgccggttgccgcccgctggcag
cggaaaattctcgacacattagcgacttatcatgagcaacatcgcgatgaacctggccct
gggcgcgaacgtctgcgacgtatggcgttgccaatggaagatgaagcgctggtactgttg
ctgattgaaaagatgcgcgaaagcggcgacatccacagccatcacggctggctgcatctg
ccagatcacaaagcgggcttcagcgaagagcagcaggccatctggcaaaaagcagagcca
ctgtttggtgacgaaccgtggtgggtgcgtgacctggcaaaagagacgggaaccgacgag
caggcaatgcgcctgactctacgccaggcggcgcagcaaggaataattaccgcgatcgtt
aaagatcgttattaccgtaacgatcggattgtcgagtttgccaatatgatccgcgatctc
gatcaggagtgtggttcaacctgcgcggcggatttccgcgatcgcttaggcgtaggccga
aagctggcaattcagattctggaatattttgaccgcattggctttacgcgtcgtcgtgga
aatgatcatttattgcgcgacgcattattatttccggaaaaataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:614
Protein Molecular Weight:68866
Protein Theoretical pI:Not Available
PDB File:2PJP
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Selenocysteine-specific elongation factor
MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAYWPQPDGRVPGFIDVPG
HEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLTGNPMLTVALTKADRVDEA
RVDEVERQVKEVLREYGFAEAKLFITAATEGRGMDALREHLLQLPEREHASQHSFRLAID
RAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRVRALHAQNQPTETANAGQRIALN
IAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHTPLTQWQPLHIHHAASHVTGRVSLL
EDNLAELVFDTPLWLADNDRLVLRDISARNTLAGARVVMLNPPRRGKRKPEYLQWLASLA
RAQSDADALSVHLERGAVNLADFAWARQLNGEGMRELLQQPGYIQAGYSLLNAPVAARWQ
RKILDTLATYHEQHRDEPGPGRERLRRMALPMEDEALVLLLIEKMRESGDIHSHHGWLHL
PDHKAGFSEEQQAIWQKAEPLFGDEPWWVRDLAKETGTDEQAMRLTLRQAAQQGIITAIV
KDRYYRNDRIVEFANMIRDLDQECGSTCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRG
NDHLLRDALLFPEK
References
External Links:
ResourceLink
Uniprot ID:P14081
Uniprot Name:SELB_ECOLI
PDB ID:2PJP
CCDB:SELB_ECOLI
General Reference:Not Available