Identification |
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Name: | Flagellar regulator flk |
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Synonyms: | Not Available |
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Gene Name: | flk |
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Enzyme Class: | Not Available |
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Biological Properties |
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General Function: | regulation of gene expression |
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Specific Function: | Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion (T3S) system. Plays a role in hindering to flip the flagellar T3S specificity switch from the rod and hook-type substrates to filament-type substrates prior to hook-basal body (HBB) completion possibly by preventing interaction of FliK with FlhB (By similarity). |
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Cellular Location: | Not Available |
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SMPDB Pathways: | Not Available |
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KEGG Pathways: | Not Available |
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Metabolites: | |
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GO Classification: | Function |
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integral component of membrane | plasma membrane | regulation of gene expression |
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Gene Properties |
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Blattner: | Not Available |
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Gene Orientation | Not Available |
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Centisome Percentage: | Not Available |
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Left Sequence End | Not Available |
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Right Sequence End | Not Available |
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Gene Sequence: | >996
atgatacaacctatttccggccctcctcctgggcaaccaccaggtcagggagataatctg
ccgtctggcacgggcaatcagcctttatccagtcagcaacgtacttcgctggaaagctta
atgacgaaagtgacctcactgacgcaacagcaaagagcagaactgtgggcgggtatcagg
cacgatattggtctgtcgggagattcaccgctgctttcgcgtcacttccctgccgctgag
cataatctggcgcaacgtctgctggccgcgcaaaaaagccattctgcccgccagctttta
gcgcaattaggggagtatttacgtctggggaataatcgtcaggcggtcacggattatatc
cgtcataactttggtcagacgccgctgaatcagctctcaccggagcaattaaaaaccatt
ctcaccctgttgcaggaagggaagatggttattccgcaaccacagcagcgcgaggcgacc
gaccgtcctttattaccggcggagcacaatgcgctaaaacagctggtgaccaaacttgcg
gcggcaacgggggaacccagcaaacagatctggcaatcgatgctggaactttccggggtg
aaagatggcgagttaattccagcgaaactgtttaaccatctggtgacctggctacaggcg
cgtcagacgctaagccagcaaaatacgccgacgctggaatcactacagatgacgctaaaa
caacctttagatgccagtgaactggcggcgttatcggcatatatccagcaaaaatatggt
ctttctgcgcaatcatcgctttcttctgcccaggccgaggatattcttaatcagctttat
caacggcgggttaaagggattgatccgcgtgttatgcaaccgctgcttaatccttttcca
ccgatgatggacacgttgcaaaatatggcaacgcgtcccgcgctgtggatactgttagtc
gcgattatcctgatgctggtctggctggttcgttaa |
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Protein Properties |
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Pfam Domain Function: | Not Available |
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Protein Residues: | 331 |
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Protein Molecular Weight: | 36667 |
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Protein Theoretical pI: | Not Available |
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Signaling Regions: | Not Available |
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Transmembrane Regions: | |
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Protein Sequence: | >Flagellar regulator flk
MIQPISGPPPGQPPGQGDNLPSGTGNQPLSSQQRTSLESLMTKVTSLTQQQRAELWAGIR
HDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQLGEYLRLGNNRQAVTDYI
RHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREATDRPLLPAEHNALKQLVTKLA
AATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWLQARQTLSQQNTPTLESLQMTLK
QPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDILNQLYQRRVKGIDPRVMQPLLNPFP
PMMDTLQNMATRPALWILLVAIILMLVWLVR |
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References |
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External Links: | |
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General Reference: | Not Available |
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