Ecotin (P23827)

Identification
Name:Ecotin
Synonyms:Not Available
Gene Name:eco
Enzyme Class:Not Available
Biological Properties
General Function:negative regulation of endopeptidase activity
Specific Function:General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. The strength of inhibition does not appear to be correlated with a particular protease specificity.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
negative regulation of endopeptidase activity
outer membrane-bounded periplasmic space
serine-type endopeptidase inhibitor activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>489
atgaagaccattctacctgcagtattgtttgccgctttcgctaccacttccgcctgggcg
gcagaaagcgtccagccactggaaaaaatcgcgccttatccacaagctgaaaaagggatg
aagcgtcaggtgattcagttaaccccgcaagaagatgaatctaccctgaaagtagaactg
ttaatcggtcagacgctggaagtcgattgcaatttgcatcgtctcggcgggaagctggaa
aacaaaacgctggaaggctggggctatgattattatgtctttgataaagtcagttccccg
gtttcaacgatgatggcctgcccggatggcaagaaagagaagaaatttgtcaccgcgtat
ctgggcgatgctggaatgctgcgttacaacagcaagctgccgatcgtggtgtatacgcca
gacaatgtagatgtgaagtaccgcgtctggaaggcggaagagaaaattgacaacgcggta
gttcgctaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:162
Protein Molecular Weight:18191
Protein Theoretical pI:Not Available
PDB File:1AZZ
Signaling Regions:
  • 1-20
Transmembrane Regions:Not Available
Protein Sequence:
>Ecotin
MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVEL
LIGQTLEVDCNLHRLGGKLENKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAY
LGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
References
External Links:
ResourceLink
Uniprot ID:P23827
Uniprot Name:ECOT_ECOLI
PDB ID:1AZZ
CCDB:ECOT_ECOLI
General Reference:Not Available