Identification
Name:DNA mismatch repair protein MutS
Synonyms:Not Available
Gene Name:mutS
Enzyme Class:Not Available
Biological Properties
General Function:regulation of DNA recombination
Specific Function:This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
Metabolites:
ECMDB IDNameView
GO Classification:
Function
adenine/cytosine mispair binding
ADP binding
ATP binding
ATPase activity
cellular response to DNA damage stimulus
cytosol
damaged DNA binding
DNA binding, bending
DNA-dependent ATPase activity
identical protein binding
mismatch repair
mismatch repair complex
mismatched DNA binding
regulation of DNA recombination
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>2562
atgagtgcaatagaaaatttcgacgcccatacgcccatgatgcagcagtatctcaggctg
aaagcccagcatcccgagatcctgctgttttaccggatgggtgatttttatgaactgttt
tatgacgacgcaaaacgcgcgtcgcaactgctggatatttcactgaccaaacgcggtgct
tcggcgggagagccgatcccgatggcggggattccctaccatgcggtggaaaactatctc
gccaaactggtgaatcagggagagtccgttgccatctgcgaacaaattggcgatccggcg
accagcaaaggtccggttgagcgcaaagttgtgcgtatcgttacgccaggcaccatcagc
gatgaagccctgttgcaggagcgtcaggacaacctgctggcggctatctggcaggacagc
aaaggtttcggctacgcgacgctggatatcagttccgggcgttttcgcctgagcgaaccg
gctgaccgcgaaacgatggcggcagaactgcaacgcactaatcctgcggaactgctgtat
gcagaagattttgctgaaatgtcgttaattgaaggccgtcgcggcctgcgccgtcgcccg
ctgtgggagtttgaaatcgacaccgcgcgccagcagttgaatctgcaatttgggacccgc
gatctggtcggttttggcgtcgagaacgcgccgcgcggactttgtgctgccggttgtctg
ttgcagtatgcgaaagatacccaacgtacgactctgccgcatattcgttccatcaccatg
gaacgtgagcaggacagcatcattatggatgccgcgacgcgtcgtaatctggaaatcacc
cagaacctggcgggtggtgcggaaaatacgctggcttctgtgctcgactgcaccgtcacg
ccgatgggcagccgtatgctgaaacgctggctgcatatgccagtgcgcgatacccgcgtg
ttgcttgagcgccagcaaactattggcgcattgcaggatttcaccgccgggctacagccg
gtactgcgtcaggtcggcgacctggaacgtattctggcacgtctggctttacgaactgct
cgcccacgcgatctggcccgtatgcgccacgctttccagcaactgccggagctgcgtgcg
cagttagaaactgtcgatagtgcaccggtacaggcgctacgtgagaagatgggcgagttt
gccgagctgcgcgatctgctggagcgagcaatcatcgacacaccgccggtgctggtacgc
gacggtggtgttatcgcatcgggctataacgaagagctggatgagtggcgcgcgctggct
gacggcgcgaccgattatctggagcgtctggaagtccgcgagcgtgaacgtaccggcctg
gacacgctgaaagttggctttaatgcggtgcacggctactacattcaaatcagccgtggg
caaagccatctggcacccatcaactacatgcgtcgccagacgctgaaaaacgccgagcgc
tacatcattccagagctaaaagagtacgaagataaagttctcacctcaaaaggcaaagca
ctggcactggaaaaacagctttatgaagagctgttcgacctgctgttgccgcatctggaa
gcgttgcaacagagcgcgagcgcgctggcggaactcgacgtgctggttaacctggcggaa
cgggcctataccctgaactacacctgcccgaccttcattgataaaccgggcattcgcatt
accgaaggtcgccatccggtagttgaacaagtactgaatgagccatttatcgccaacccg
ctgaatctgtcgccgcagcgccgcatgttgatcatcaccggtccgaacatgggcggtaaa
agtacctatatgcgccagaccgcactgattgcgctgatggcctacatcggcagctatgta
ccggcacaaaaagtcgagattggacctatcgatcgcatctttacccgcgtaggcgcggca
gatgacctggcgtccgggcgctcaacctttatggtggagatgactgaaaccgccaatatt
ttacataacgccaccgaatacagtctggtgttaatggatgagatcgggcgtggaacgtcc
acctacgatggtctgtcgctggcgtgggcgtgcgcggaaaatctggcgaataagattaag
gcattgacgttatttgctacccactatttcgagctgacccagttaccggagaaaatggaa
ggcgtcgctaacgtgcatctcgatgcactggagcacggcgacaccattgcctttatgcac
agcgtgcaggatggcgcggcgagcaaaagctacggcctggcggttgcagctctggcaggc
gtgccaaaagaggttattaagcgcgcacggcaaaagctgcgtgagctggaaagcatttcg
ccgaacgccgccgctacgcaagtggatggtacgcaaatgtctttgctgtcagtaccagaa
gaaacttcgcctgcggtcgaagctctggaaaatcttgatccggattcactcaccccgcgt
caggcgctggagtggatttatcgcttgaagagcctggtgtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:853
Protein Molecular Weight:95245
Protein Theoretical pI:Not Available
PDB File:1E3M
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>DNA mismatch repair protein MutS
MSAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGA
SAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTIS
DEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLY
AEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCL
LQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVT
PMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAGLQPVLRQVGDLERILARLALRTA
RPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVR
DGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRG
QSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLE
ALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANP
LNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAA
DDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIK
ALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAG
VPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPR
QALEWIYRLKSLV
References
External Links:
ResourceLink
Uniprot ID:P23909
Uniprot Name:MUTS_ECOLI
PDB ID:1E3M
CCDB:MUTS_ECOLI
General Reference:Not Available