Identification
Name:tRNA modification GTPase MnmE
Synonyms:Not Available
Gene Name:mnmE
Enzyme Class:Not Available
Biological Properties
General Function:xenobiotic metabolic process
Specific Function:Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
chaperone-mediated protein folding
cytoplasm
cytosol
GDP binding
GTP binding
GTPase activity
plasma membrane
potassium ion binding
response to pH
tRNA methylation
tRNA wobble uridine modification
xenobiotic metabolic process
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1365
atgagcgataatgacactatcgtagcccaggccacgcctccgggacgtggcggcgttggc
atcctgcgcatctccggcttcaaagcccgtgaagttgccgaaaccgtgctgggtaaactg
cctaagccgcgctacgccgattatcttccgtttaaagacgccgacggcagcgtgctcgat
caggggattgcgctatggttccctggcccgaactcgttcaccggcgaagatgtgctggaa
ctgcaaggtcatggcggtccggtgatcctcgacctgctgttaaaacgcattctgaccatt
cccggcctgcggattgctcgccctggtgagttttccgaacgcgcgtttcttaacgataaa
cttgacttagcccaggccgaggcgattgccgatcttatcgacgccagttcggaacaggcg
gcccgttcggcacttaactcgctgcaaggcgcattctccgcacgggttaatcatctggta
gaagccctcacccacttgcgcatttacgtcgaagcggcaattgatttccccgatgaagag
atcgatttcctctccgacggaaaaattgaagcccagctcaatgacgttattgccgatctt
gatgcagtgcgtgctgaagcacgtcagggtagtttgttgcgcgaagggatgaaagtggtg
attgccggacgtcctaacgccggtaaatcgagcctgttaaacgcgctggcggggcgtgaa
gcggcaatcgtaaccgatatcgccggaactacgcgtgacgtgctgcgtgagcatatccac
attgacggaatgccgctgcatatcatcgataccgccgggctacgtgaagccagtgacgaa
gtagaacgtattggtatcgagcgcgcgtggcaggaaattgaacaggccgaccgcgtgctg
tttatggtcgatggcaccacaacagacgccgtggatccggcagagatctggccggaattt
attgcccgtctgccagcgaaactgccgatcaccgtggtgcgcaataaagccgatatcacc
ggcgaaacgctgggaatgagtgaagtgaacggtcacgcgttaattcgtctctcggcaagg
actggtgaaggcgtggacgtgctgcgtaaccatctcaaacagagcatgggctttgacacc
aacatggaaggcggcttcctggcgcgtcgtcgccacctacaggcgctggaacaggcagcg
gaacatctacaacagggcaaagcgcaactgttgggagcctgggcaggtgaactgctggcg
gaagagttgcgtctggcacagcagaacttaagcgaaatcaccggggaatttacttcagac
gacctgctggggcggattttctccagcttctgtattggtaagtaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:454
Protein Molecular Weight:49230
Protein Theoretical pI:Not Available
PDB File:1RFL
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>tRNA modification GTPase MnmE
MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPRYADYLPFKDADGSVLD
QGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDK
LDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEE
IDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGRE
AAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVL
FMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVRNKADITGETLGMSEVNGHALIRLSAR
TGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALEQAAEHLQQGKAQLLGAWAGELLA
EELRLAQQNLSEITGEFTSDDLLGRIFSSFCIGK
References
External Links:
ResourceLink
Uniprot ID:P25522
Uniprot Name:MNME_ECOLI
PDB ID:1RFL
CCDB:MNME_ECOLI
General Reference:Not Available