Identification
Name:Inorganic triphosphatase
Synonyms:Not Available
Gene Name:ygiF
Enzyme Class:
Biological Properties
General Function:metabolic process
Specific Function:Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), which could be cytotoxic because of its high affinity for calcium ion, thereby interfering with calcium signaling. It also hydrolyzes slowly thiamine triphosphatase (ThTP). YgiF is a specific PPPase, but it contributes only marginally to the total PPPase activity in E.coli, where the main enzyme responsible for hydrolysis of PPPi is inorganic pyrophosphatase (PPase).
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
KEGG Reactions:
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb
Metabolites:
ECMDB IDNameView
GO Classification:
Function
metabolic process
triphosphatase activity
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1302
atggctcaggaaatcgaattaaagtttattgttaatcacagtgccgttgaggcgttgcgt
gaccatctcaatacgctgggcggcgagcaccatgaccccgtgcagttgctgaatatttac
tacgaaacgccggataactggctgcgtgggcacgatatgggcttacgtattcgtggcgaa
aacggtcgctatgagatgaccatgaaagttgcaggaagagtgacaggcggcttacatcag
cgcccggaatataacgtggcgttgagcgaaccgacgctcgacctggcgcagttaccgacg
gaagtctggccgaacggcgaattgcccgccgatctcgcctcccgcgtgcagccgctgttc
agcaccgatttttatcgcgaaaaatggctggtggcggtcgatggtagccaaattgaaatc
gccctcgaccagggggaagtgaaagcgggtgaatttgctgaacctatctgtgagctggaa
ctggaactgcttagcggcgacacgcgcgcggtgctgaaactggcgaaccaactggtatcg
caaaccggattacgccagggcagcctgagcaaagcggcgcgtggctatcatctggcgcag
ggcaatccggcgcgtgaaatcaaaccgaccaccattttgcatgttgcggcaaaagccgat
gtggaacaggggctggaagcggcgctcgagctggcgttagcgcaatggcagtatcatgaa
gaactgtgggtacgcggcaacgatgcggcgaaagaacaggtgctggcagccattagcctg
gtccgtcatacgctgatgctgttcggtggtattgtgccgcgtaaagcgagcactcactta
cgtgatctgctgactcaatgcgaggcgaccattgcttctgcggtgtctgccgtgacggcg
gtctactctaccgaaacggcaatggcgaagctggcgttgaccgaatggttggtaagcaaa
gcatggcagccatttttagatgccaaagcgcagggcaaaatcagcgactccttcaaacgc
tttgccgatatccatctttcccgccatgccgctgaactgaaaagcgttttctgccagccg
ttaggcgatcgctaccgtgaccagttgccacgcctgacgcgtgatattgactcaatactg
ttgctggcgggttactatgatcctgtcgtcgcgcaagcctggctggagaactggcagggg
ctgcatcacgctattgcgaccgggcaacgcatcgaaattgaacatttccgtaatgaggca
aacaatcaggaaccgttctggttgcacagcggaaaacgttaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:433
Protein Molecular Weight:48388
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>Inorganic triphosphatase
MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGE
NGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLF
STDFYREKWLVAVDGSQIEIALDQGEVKAGEFAEPICELELELLSGDTRAVLKLANQLVS
QTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAALELALAQWQYHE
ELWVRGNDAAKEQVLAAISLVRHTLMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTA
VYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQP
LGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQGLHHAIATGQRIEIEHFRNEA
NNQEPFWLHSGKR
References
External Links:
ResourceLink
Uniprot ID:P30871
Uniprot Name:3PASE_ECOLI
CCDB:3PASE_ECOLI
General Reference:Not Available