ECMDB

Identification

Name:

Ribosomal RNA large subunit methyltransferase J

Synonyms:

Not Available

Gene Name:

rlmJ

Enzyme Class:

2.1.1.266

Biological Properties

General Function:

rRNA base methylation

Specific Function:

Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.

Cellular Location:

Not Available

SMPDB Pathways:

Not Available

KEGG Pathways:

Not Available

Metabolites:

ECMDB ID	Name	View

GO Classification:

Function
23S rRNA (adenine(2030)-N(6))-methyltransferase activity
carbon utilization
RNA binding
rRNA (adenine-N6-)-methyltransferase activity
rRNA base methylation

Gene Properties

Blattner:

Not Available

Gene Orientation

Not Available

Centisome Percentage:

Not Available

Left Sequence End

Not Available

Right Sequence End

Not Available

Gene Sequence:

>843
atgctcagttatcgccacagctttcacgctggcaaccacgccgacgtccttaaacatacc
gttcagagcctgatcatcgagtcgctgaaagagaaagataaaccgtttctctatctcgac
acccacgcaggggccgggcgttatcagttaggcagcgaacatgccgagcgtaccggcgaa
tatctcgaaggcatcgcccgtatctggcagcaggacgatttgcccgcagaactggaggcg
tacatcaatgtggtaaaacacttcaaccgtagcggtcagttgcgttactaccccggttcg
ccgttgattgctcgcctgctactgcgtgaacaggacagcctgcaactgaccgaactgcac
ccgagcgattacccgttgttgcgttctgaatttcagaaagatagccgtgcgcgtgtcgaa
aaagccgacggtttccagcagcttaaggccaaactgccgccggtttcccgccgtggttta
atccttatcgacccgccgtatgaaatgaaaactgactatcaagcggtggtcagcgggata
gcagaaggttacaaacgtttcgccactggtatttacgcactgtggtatccggtggtgctg
cgtcagcaaattaagcgcatgatccacgatctggaagcgaccggtattcgcaaaattctg
caaattgaactggcggtactgccagacagcgatcgccgtggcatgaccgcttccggcatg
attgtgattaacccgccgtggaaactggaacaacagatgaataacgtgctgccgtggctg
cacagcaaactggttccggcaggcaccgggcacgccaccgtaagctggatcgtgccggag
taa

Protein Properties

Pfam Domain Function:

Not Available

Protein Residues:

280

Protein Molecular Weight:

31941

Protein Theoretical pI:

Not Available

PDB File:

4BLU

Signaling Regions:

Not Available

Transmembrane Regions:

Not Available

Protein Sequence:

>Ribosomal RNA large subunit methyltransferase J
MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAGAGRYQLGSEHAERTGE
YLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPLIARLLLREQDSLQLTELH
PSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGLILIDPPYEMKTDYQAVVSGI
AEGYKRFATGIYALWYPVVLRQQIKRMIHDLEATGIRKILQIELAVLPDSDRRGMTASGM
IVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSWIVPE

References

External Links:

Resource	Link
Uniprot ID:	P37634
Uniprot Name:	RLMJ_ECOLI
PDB ID:	4BLU
CCDB:	RLMJ_ECOLI

General Reference:

Not Available

Ribosomal RNA large subunit methyltransferase J (P37634)