| Identification |
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| Name: | Anti-adapter protein IraD |
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| Synonyms: | Not Available |
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| Gene Name: | iraD |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | positive regulation of transcription, DNA-templated |
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| Specific Function: | Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| anti-sigma factor antagonist activity | | cellular response to DNA damage stimulus | | cytoplasm | | negative regulation of protein catabolic process | | positive regulation of transcription, DNA-templated |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >393
atgatgcgacaatcacttcaggctgttttacctgaaatttcaggcaataaaacgtcatcg
ctgcgtaaatcggtatgcagcgatctcctcactctttttaattctcctcattcggcatta
ccgtcattacttgtttcaggcatgcccgagtggcaagtgcataacccgagcgacaaacat
ctccagagctggtattgccgtcagctgcgttctgcactgttatttcatgagccacggatt
gcggcgttgcaggttaatttgaaagaagcgtactgccacactctggcgatcagccttgag
ataatgctgtaccacgacgatgaaccgctaacgtttgatctggtctgggataatggcggt
tggcgcagtgcgacgctggagaatgtcagctaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 130 |
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| Protein Molecular Weight: | 14746 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Anti-adapter protein IraD
MMRQSLQAVLPEISGNKTSSLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKH
LQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDEPLTFDLVWDNGG
WRSATLENVS |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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