Identification
Name:HTH-type transcriptional regulator YjiE
Synonyms:Not Available
Gene Name:yjiE
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Protects cells from HOCl (hypochlorite) stress but not peroxide or diamide stress. Decreases the intracellular load of reactive oxygen species by up-regulating genes involved in methionine and cysteine biosynthesis and down-regulating Fur-regulated genes involved in iron acquisition. Has also been suggested to down-regulate expression of the flagellar regulon, decreasing motility, but this activity was not confirmed in a second study (PubMed:22223481).
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
bacterial-type RNA polymerase regulatory region DNA binding
identical protein binding
regulation of transcription, DNA-templated
sequence-specific DNA binding transcription factor activity
transcription regulatory region sequence-specific DNA binding
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>912
atggatgactgtggtgcgattttgcataatattgaaaccaaatggctttatgattttctg
accctggaaaaatgccgcaatttttcccaggcggcagtcagtcgcaacgtctcgcaaccg
gcattcagccgccgcatccgtgcgctggaacaggcgattggtgttgaattgtttaaccgc
caggtaacgccgctgcaactctcagaacaagggaaaatcttccattcgcagatccgccat
ctgttgcaacagttagagagcaatctggcagagctgcgtggcggcagcgattacgcgcaa
cgaaaaatcaagatagccgctgcacactctctttccctcgggctgttaccgtccattatc
agccagatgccgccgctctttacctgggcaattgaagctattgatgtcgatgaagcggtc
gataaactgcgtgaagggcaaagtgactgtattttttcctttcacgacgaagatttgctg
gaagcgccgtttgaccacattcgcttatttgaatctcaattgttccctgtctgcgccagt
gacgaacacggagaagcactttttaacctcgcgcagccacactttccgttactgaattac
agccgcaactcctacatggggcgattgattaatcgcaccctgacgcgccacagtgagtta
agtttcagcaccttttttgtctcttcgatgagcgagcttttaaagcaggttgccctcgac
ggctgtgggattgcctggctgccggagtacgccatccaacaagaaattcgcagcgggaag
ctcgttgtactgaatcgggacgaactggtgatcccgattcaggcctatgcataccggatg
aatacccgcatgaatcccgttgccgaacgcttctggcgtgaactgcgcgagctggagatt
gtgcttagctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:303
Protein Molecular Weight:34710
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>HTH-type transcriptional regulator YjiE
MDDCGAILHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSRRIRALEQAIGVELFNR
QVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRKIKIAAAHSLSLGLLPSII
SQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLLEAPFDHIRLFESQLFPVCAS
DEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHSELSFSTFFVSSMSELLKQVALD
GCGIAWLPEYAIQQEIRSGKLVVLNRDELVIPIQAYAYRMNTRMNPVAERFWRELRELEI
VLS
References
External Links:
ResourceLink
Uniprot ID:P39376
Uniprot Name:YJIE_ECOLI
CCDB:YJIE_ECOLI
General Reference:Not Available