| Identification |
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| Name: | FMN-dependent NADH-azoreductase |
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| Synonyms: | Not Available |
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| Gene Name: | azoR |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | response to oxidative stress |
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| Specific Function: | Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity. The enzyme can reduce ethyl red and methyl red, but is not able to convert sulfonated azo dyes. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| azobenzene reductase activity | | electron carrier activity | | FMN binding | | FMN reductase activity | | oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor | | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | | response to oxidative stress |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >606
atgagcaaggtattagttcttaaatccagcatcctggcagggtactctcagtctaatcag
ttgtccgattattttgttgaacaatggcgcgaaaagcactccgctgatgaaatcaccgtt
cgcgacctggctgcaaatccgattccggtactggatggcgaactggttggcgctctgcgt
ccgagcgatgcgccgctgactccgcgtcagcaggaagctctggcactttccgatgagttg
attgccgagctgaaagcccacgacgttatcgttattgcggcaccgatgtataacttcaac
atctcgactcagttgaaaaactattttgacctggttgcccgcgcaggcgttactttccgc
tataccgagaacggtccggaaggtctggtaacgggtaaaaaagccatcgttattaccagc
cgcggcgggatccacaaagatggaccaacggacctggtgacgccgtatctgtccacgttc
ctcggctttatcggcattaccgatgtgaaatttgtcttcgccgaagggatcgcatacggt
ccggaaatggcagcgaaagcacagtctgacgcaaaagcagccatcgacagcattgtttct
gcataa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 201 |
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| Protein Molecular Weight: | 21657 |
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| Protein Theoretical pI: | Not Available |
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| PDB File: | 1TIK |
| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >FMN-dependent NADH-azoreductase
MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALR
PSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFR
YTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYG
PEMAAKAQSDAKAAIDSIVSA |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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