Identification
Name:CsgBAC operon transcriptional regulatory protein
Synonyms:Not Available
Gene Name:csgD
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA transcription. Low-level constitutive expression confers an adherent curli fimbriae-expressing phenotype, up-regulates 10 genes and down-regulates 14 others.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding
plasma membrane
positive regulation of DNA-templated transcription, initiation
regulation of single-species biofilm formation
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>651
atgtttaatgaagtccatagtattcatggtcatacattattgttgatcactaaatcttct
ttgcaggcgacagctctcttgcagcaccttaaacaatcgctggcaattacaggaaaatta
cataatattcaacgttctctggacgatatctcttcaggctctattattcttctggatatg
atggaagcggataaaaagcttatccattattggcaggatactttgagcaggaaaaacaac
aatatcaaaatattgttgctaaatacgcctgaagattacccgtaccgcgacattgaaaac
tggcctcatatcaacggcgttttttattccatggaggatcaagaacgtgttgtcaatggg
ttgcaaggcgtcctgcgcggcgaatgctactttacgcaaaagcttgccagctacctgatt
acgcattcaggtaactatcgttataacagcacggaatcagccctccttactcatcgggaa
aaagagatcctgaataagctgcgtatcggcgcgtctaataacgagatcgctcgttcgttg
ttcatcagcgaaaatacggttaaaacgcatctttataatcttttcaagaagatagccgta
aaaaaccggacacaagcggtttcctgggcaaacgataacctcaggcgataa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:216
Protein Molecular Weight:24935
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>CsgBAC operon transcriptional regulatory protein
MFNEVHSIHGHTLLLITKSSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDM
MEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNG
LQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSL
FISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
References
External Links:
ResourceLink
Uniprot ID:P52106
Uniprot Name:CSGD_ECOLI
CCDB:CSGD_ECOLI
General Reference:Not Available