| Identification |
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| Name: | Regulator of sigma S factor FliZ |
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| Synonyms: | Not Available |
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| Gene Name: | fliZ |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | regulation of nucleic acid-templated transcription |
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| Specific Function: | During the post-exponential growth phase transiently interferes with RpoS (sigma S) activity without affecting expression of RpoS itself. It is probably not an anti-sigma factor as its overexpression is detrimental in rapidly growing cells where there is almost no sigma S factor. There is a strong overlap between Crl-activated genes and FliZ-down-regulated genes. FliZ acts as a timing device for expression of the genes for the adhesive curli fimbriae by indirectly decreasing expression of the curli regulator CsgD. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| core promoter binding | | DNA integration | | regulation of bacterial-type flagellum-dependent cell motility | | regulation of nucleic acid-templated transcription | | sigma factor antagonist activity |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >552
atgatggtgcagcacctgaaaagacggccattaagccgctatcttaaagactttaaacac
agccagacccattgcgcgcattgccgtaaattactcgatcgcattaccttagttcgcgac
ggcaaaatagtgaataaaatcgagatttcccgcctggacacgctgcttgatgaaaatggc
tggcaaacggaacaaaaatcatgggcggcattgtgccgattttgcggtgatttacattgc
aaaacgcagagtgattttttcgatattatcggctttaagcaatttctttttgagcaaact
gaaatgagcccaggtacggtgcgtgaatatgtcgttcgtttgcgccgtttggggaatcat
ctacacgagcaaaatatttccctcgatcagctgcaggacggtttccttgatgaaatcctc
gccccgtggctgcccaccaccagcaccaacaattaccgcatcgcgttacggaagtatcaa
cactatcagcgccaaacctgtaccagacttgtgcagaaatcctccagcctgccttcttct
gatatatattaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 183 |
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| Protein Molecular Weight: | 21657 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | Not Available |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Regulator of sigma S factor FliZ
MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIVNKIEISRLDTLLDENG
WQTEQKSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEMSPGTVREYVVRLRRLGNH
LHEQNISLDQLQDGFLDEILAPWLPTTSTNNYRIALRKYQHYQRQTCTRLVQKSSSLPSS
DIY |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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