| Identification |
|---|
| Name: | Fe/S biogenesis protein NfuA |
|---|
| Synonyms: | Not Available |
|---|
| Gene Name: | nfuA |
|---|
| Enzyme Class: | Not Available |
|---|
| Biological Properties |
|---|
| General Function: | response to oxidative stress |
|---|
| Specific Function: | Involved in iron-sulfur cluster biogenesis under severe conditions such as iron starvation or oxidative stress. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. Required for E.coli to sustain oxidative stress and iron starvation. Also necessary for the use of extracellular DNA as the sole source of carbon and energy. |
|---|
| Cellular Location: | Not Available |
|---|
| SMPDB Pathways: | Not Available |
|---|
| KEGG Pathways: | Not Available |
|---|
| Metabolites: | |
|---|
| GO Classification: | | Function |
|---|
| 4 iron, 4 sulfur cluster binding | | carbon utilization | | cellular response to iron ion starvation | | iron ion binding | | iron-sulfur cluster assembly | | protein maturation by iron-sulfur cluster transfer | | response to oxidative stress |
|
|---|
| Gene Properties |
|---|
| Blattner: | Not Available |
|---|
| Gene Orientation | Not Available |
|---|
| Centisome Percentage: | Not Available |
|---|
| Left Sequence End | Not Available |
|---|
| Right Sequence End | Not Available |
|---|
| Gene Sequence: | >576
atgatccgtatttccgatgctgcacaagcgcactttgccaaactgctggcaaatcaggaa
gaagggacacaaatccgcgtatttgtgattaaccctggcacgcctaacgctgaatgtggc
gtttcttattgtccgccggacgctgtggaagccaccgacacagccctgaaatttgacctg
ctgaccgcgtatgttgatgagttaagcgcaccatacctggaagatgcagagatcgatttt
gttaccgaccagttgggttcccagttaacgctgaaagccccgaacgccaaaatgcgtaaa
gtggcagacgatgcaccgctgatggagcgcgtggagtatatgctgcagtcgcagatcaac
ccacagcttgctggtcacggtggtcgcgtttcgctgatggaaatcaccgaagacggttac
gccattctgcaatttggcggcggctgtaacggttgttccatggtcgatgtgacgctgaaa
gaagggatcgagaagcagctgctgaacgaattcccggagctgaaaggtgtgcgcgatctc
accgaacaccagcgcggcgaacactcctactactaa |
|---|
| Protein Properties |
|---|
| Pfam Domain Function: | Not Available |
|---|
| Protein Residues: | 191 |
|---|
| Protein Molecular Weight: | 20997 |
|---|
| Protein Theoretical pI: | Not Available |
|---|
| Signaling Regions: | Not Available |
|---|
| Transmembrane Regions: | Not Available |
|---|
| Protein Sequence: | >Fe/S biogenesis protein NfuA
MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDL
LTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQIN
PQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDL
TEHQRGEHSYY |
|---|
| References |
|---|
| External Links: | |
|---|
| General Reference: | Not Available |
|---|
