Identification
Name:HTH-type transcriptional regulator GadW
Synonyms:Not Available
Gene Name:gadW
Enzyme Class:Not Available
Biological Properties
General Function:transcription, DNA-templated
Specific Function:Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC. Repression occurs directly or via the repression of the expression of gadX. Activation occurs directly by the binding of GadW to the gadA and gadBC promoters.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cellular response to DNA damage stimulus
DNA binding
protein-DNA complex
regulation of transcription, DNA-templated
sequence-specific DNA binding
sequence-specific DNA binding transcription factor activity
transcription, DNA-templated
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>729
atgactcatgtctgctcggtgatcctcattcgtcgttcattcgatatttatcatgaacag
caaaaaatatcgctgcataacgagagtattctgctgctggagaaaaatttggcagacgat
tttgcgttttgttcaccggatacgcgacgactggatatcgatgagctgacagtttgccat
tacttacaaaatattcgtcagctaccacgcaatttagggttacacagcaaagaccgtttg
ttaattaaccagtcaccccccatgccgctggtgacggcgatttttgatagcttcaatgaa
tccggggtaaattcaccgatactgagcaatatgctctacctttcctgtttatcgatgttt
tctcataagaaagaactgatccccttacttttcaatagcatcagcactgtttcaggaaaa
gttgaacgccttattagctttgatatcgccaaacgttggtatctgcgcgatatcgcggaa
agaatgtataccagcgagagtctaatcaaaaaaaagttgcaggatgaaaatacctgtttc
agtaaaatattactcgcctccaggatgtcgatggccagacgattactcgagttacgtcaa
attcctctgcatactattgcggaaaaatgtggctatagcagtacatcgtactttataaac
acatttcgacaatattatggtgtaacgccacatcagtttgcgcaacattcgccaggtacc
ttttcctga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:242
Protein Molecular Weight:28028
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>HTH-type transcriptional regulator GadW
MTHVCSVILIRRSFDIYHEQQKISLHNESILLLEKNLADDFAFCSPDTRRLDIDELTVCH
YLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESGVNSPILSNMLYLSCLSMF
SHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAERMYTSESLIKKKLQDENTCF
SKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYFINTFRQYYGVTPHQFAQHSPGT
FS
References
External Links:
ResourceLink
Uniprot ID:P63201
Uniprot Name:GADW_ECOLI
CCDB:GADW_ECOLI
General Reference:Not Available