| Identification |
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| Name: | Beta-barrel assembly-enhancing protease |
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| Synonyms: | Not Available |
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| Gene Name: | bepA |
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| Enzyme Class: | Not Available |
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| Biological Properties |
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| General Function: | chaperone-mediated protein folding |
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| Specific Function: | Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. Promotes disulfide rearrangement of LptD during its biogenesis, and proteolytic degradation of LptD and BamA when their proper assembly is compromised. May facilitate membrane attachment of LoiP under unfavorable conditions. |
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| Cellular Location: | Not Available |
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| SMPDB Pathways: | Not Available |
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| KEGG Pathways: | Not Available |
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| Metabolites: | |
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| GO Classification: | | Function |
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| chaperone-mediated protein folding | | membrane | | metalloendopeptidase activity | | metallopeptidase activity | | outer membrane-bounded periplasmic space | | zinc ion binding |
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| Gene Properties |
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| Blattner: | Not Available |
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| Gene Orientation | Not Available |
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| Centisome Percentage: | Not Available |
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| Left Sequence End | Not Available |
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| Right Sequence End | Not Available |
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| Gene Sequence: | >1464
atgttcaggcagttgaaaaaaaacctggttgcaaccctcattgctgctatgaccattggt
caggtagccccggcgtttgccgacagcgcagacaccttgccggatatgggaacctccgca
ggaagcacgctttccattggtcaggaaatgcagatgggcgactattatgtccgccagcta
cgcggcagcgcgccgttaattaatgacccgctgttaacgcaatatattaattcgctgggg
atgcgtctggtttcgcatgccaattcggttaagacaccgtttcatttttttctgatcaac
aacgacgaaattaacgcctttgctttctttggcggcaacgtggtgctgcactctgccctg
ttccgttattccgataacgaaagtcaactggcttcagttatggcgcacgaaatctcccac
gtcacccaacgtcacctggcgcgagcgatggaagatcagcagcgcagcgcgccgctgacc
tgggtcggcgcgttaggttctattttactggcgatggccagtccgcaggcggggatggcg
gcgctgaccggtacactggcgggaacgcgtcaggggatgatcagtttcacccagcaaaat
gaacaggaagcggaccgcattggtattcaggtgctgcaacgctcgggattcgatccgcag
gcgatgccaaccttcctcgaaaaattactcgatcaggcgcgttactcctcgcgcccgccg
gaaattttattgactcacccgttgccggaaagtcgtctggcagatgcccgcaaccgtgct
aatcagatgcgcccgatggtggtgcagtcgtcggaagatttctatctggcgaaagcgcgc
acactggggatgtataattccggacgtaaccagctcaccagtgatttgctggatgaatgg
gcgaaaggaaacgttcgtcagcaacgagcagcacaatatggtcgtgctttacaggcgatg
gaagccaataaatacgacgaggcgcgtaaaacgctgcaaccgttactggcggcagaacct
ggcaacgcatggtatctcgatctggctactgatatcgatcttgggcaaaacaaagccaat
gaggcgatcaatcgtctgaaaaatgcccgcgatttacgcaccaatccggtgttgcagctc
aacctggcgaacgcttatttgcaaggcggtcaaccacaagaagcggccaatattctgaat
cgctacacctttaataataaagatgacagcaacggctgggatttgctggcacaggcggaa
gccgcgctaaataaccgcgatcaggagctggctgcgcgagcagaaggttatgcgctcgcc
ggacgactcgatcaggccatttcgctgttgagtagcgccagttcgcaggtgaaattaggc
agcctgcaacaagcgcgttacgatgcgcgcatcgaccagttgcgccagctgcaggaacgc
tttaagccttataccaagatgtaa |
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| Protein Properties |
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| Pfam Domain Function: | Not Available |
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| Protein Residues: | 487 |
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| Protein Molecular Weight: | 53907 |
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| Protein Theoretical pI: | Not Available |
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| Signaling Regions: | |
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| Transmembrane Regions: | Not Available |
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| Protein Sequence: | >Beta-barrel assembly-enhancing protease
MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQL
RGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSAL
FRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLTWVGALGSILLAMASPQAGMA
ALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEW
AKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKAN
EAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAE
AALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
FKPYTKM |
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| References |
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| External Links: | |
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| General Reference: | Not Available |
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